Thilagar Gobinath, Samuthirapandian Ravichandran
Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai, Tamil Nadu, India.
Toxicol Rep. 2020 Feb 8;7:296-303. doi: 10.1016/j.toxrep.2020.02.006. eCollection 2020.
In the current study heavy metal removing capability and antioxidant properties of chitosan supplemented diet tested in lead poisoning induced in comparison with and standard fish diet. fishes weighed (20 ± 2gm) were purchased from a local commercial fish pond and acclimated to the laboratory conditions for 10 days. After that fish were dived into four groups, each group received respective feed throughout the experimental period. The fish fed with standard diet exhibited drastic weakening of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GR), glutathione peroxidase (GPx), ascorbic acid, α- tocopherol and β-carotene and also displayed abnormal histological changes in gills, liver, and intestine. The fish fed with a chitosan supplemented diet for 10 days showed substantial enhancements in antioxidant levels and also normal histological structures of organs in the fish.
在本研究中，对壳聚糖补充饲料在铅中毒诱导的鱼类中的重金属去除能力和抗氧化特性进行了测试，并与标准鱼类饲料进行了比较。从当地商业鱼塘购买体重为（20±2克）的鱼类，并使其适应实验室条件10天。之后，将鱼分为四组，在整个实验期间每组接受相应的饲料。喂食标准饲料的鱼超氧化物歧化酶（SOD）、过氧化氢酶（CAT）、还原型谷胱甘肽（GR）、谷胱甘肽过氧化物酶（GPx）、抗坏血酸、α-生育酚和β-胡萝卜素显著减弱，鳃、肝脏和肠道也出现异常组织学变化。喂食壳聚糖补充饲料10天的鱼抗氧化水平显著提高，器官组织学结构也正常。
