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韩国多中心研究:乙状结肠扭转的临床转归及其复发的危险因素。

Clinical outcomes of sigmoid volvulus and risk factors for its recurrence: a multicenter study in Korea.

机构信息

Department of Surgery, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, 40, Sukwoo-Dong, Hwaseong-Si, Gyeonggi-Do, 445-170, Republic of Korea.

Department of Surgery, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon- Si, 200-950, Republic of Korea.

出版信息

Int J Colorectal Dis. 2020 Oct;35(10):1841-1847. doi: 10.1007/s00384-020-03526-w. Epub 2020 Feb 18.

Abstract

PURPOSE

Sigmoid volvulus is one of the leading causes of colonic obstruction. The aims of this study were to review the treatment characteristics and clinical outcomes of patients diagnosed with sigmoid volvulus over 10 years at five university-affiliated hospitals in Korea, and to identify possible risk factors for its recurrence.

METHODS

Retrospective review was performed for medical records of patients who were diagnosed with sigmoid volvulus and managed surgically or conservatively at the five Hallym University-affiliated hospitals between January 2005 and July 2018.

RESULTS

A total of 69 patients were diagnosed, of whom 11 patients underwent emergency surgery and 58 patients were conservatively managed. Non-operative management was successful in 53 of 58 patients (91.4%) at initial admission. Of the non-operative managed patients, six patients required emergency surgery due to unsuccessful decompression or recurrence whereas 23 patients underwent regular surgery for definitive treatment. And overall recurrence rate and mortality rate were 25.8% (15/58) and 1.7% (1/58), respectively. A total of 40 patients underwent surgery; 23 underwent regular surgery and 17 underwent emergency surgery. Restoration of bowel continuity was more frequently performed in the regular surgery group than in the emergency surgery group (87.0% vs 52.9%, P = 0.03). In multivariable analysis, only non-operative management at the initial admission (P = 0.029) was independently associated with recurrence.

CONCLUSION

Although non-operative treatment can be initially attempted, surgery is required for preventing recurrence. Regular surgery should be considered to restore continuity of the bowel.

摘要

目的

乙状结肠扭转是结肠梗阻的主要原因之一。本研究旨在回顾韩国 5 所大学附属医院 10 余年来诊断为乙状结肠扭转的患者的治疗特点和临床结局,并确定其复发的可能危险因素。

方法

回顾性分析 2005 年 1 月至 2018 年 7 月期间在 5 所翰林大学附属医院接受手术或保守治疗的乙状结肠扭转患者的病历。

结果

共诊断出 69 例患者,其中 11 例患者行急诊手术,58 例患者行保守治疗。58 例非手术治疗患者中,53 例(91.4%)在初次入院时治疗成功。在非手术治疗的患者中,有 6 例因减压失败或复发而需要急诊手术,而有 23 例患者因确定性治疗而行常规手术。总的复发率和死亡率分别为 25.8%(15/58)和 1.7%(1/58)。共有 40 例患者接受了手术;23 例行常规手术,17 例行急诊手术。常规手术组较急诊手术组更常进行肠连续性恢复(87.0% vs 52.9%,P=0.03)。多变量分析显示,仅初次入院时的非手术治疗(P=0.029)与复发独立相关。

结论

虽然可以尝试初始非手术治疗,但为了预防复发,需要手术。应考虑常规手术来恢复肠道的连续性。

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