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腹腔镜垂直袖状胃切除术作为治疗糖尿病成人的一种选择。

Laparoscopic Vertical Sleeve Gastrectomy as a Treatment Option for Adults with Diabetes Mellitus.

机构信息

Center for Advanced Laparoscopic General & Bariatric Surgery, MedStar Washington Hospital Center and Georgetown University School of Medicine, Washington, DC, USA.

出版信息

Adv Exp Med Biol. 2021;1307:299-320. doi: 10.1007/5584_2020_487.

Abstract

Obesity is a major factor in the worldwide rise in the prevalence of type 2 diabetes mellitus. The obesity "epidemic" will require novel, effective interventions to permit both the prevention and treatment of diabetes caused by obesity. Laparoscopic vertical sleeve gastrectomy is a newer bariatric surgical procedure with a lower risk of complications (compared to Roux-en-Y gastric bypass surgery). Based in part on restriction of daily caloric intake, sleeve gastrectomy has a major role in inducing significant weight loss and weight loss is maintained for at least 10 years. Prior studies have supported the utility of the vertical sleeve gastrectomy for the treatment and management of subgroups of individuals with diabetes mellitus. There are reports of 11% to 76.9% of obese individuals discontinuing use of diabetic medications in studies lasting up to 8 years after vertical sleeve gastrectomy. Major ongoing issues include the preoperative determination of the suitability of diabetic patients to undergo this bariatric surgical procedure. Understanding how this surgical procedure is performed and the resulting anatomy is important when vertical sleeve gastrectomy is being considered as a treatment option for diabetes. In the postoperative periods, specific macronutrient goals and micronutrient supplements are important for successful and safer clinical results. An understanding of immediate- and long term- potential complications is important for reducing the potential risks of vertical sleeve gastrectomy. This includes the recognition and treatment of postoperative nutritional deficiencies and disorders. Vertical sleeve gastrectomy is a component of a long term, organized program directed at treating diabetes related to obesity. This approach may result in improved patient outcomes when vertical sleeve gastrectomy is performed to treat type 2 diabetes in obese individuals.

摘要

肥胖是全球 2 型糖尿病患病率上升的一个主要因素。肥胖“流行”将需要新的、有效的干预措施,以预防和治疗肥胖引起的糖尿病。腹腔镜垂直袖状胃切除术是一种较新的减肥手术,其并发症风险较低(与 Roux-en-Y 胃旁路手术相比)。基于限制每日热量摄入,袖状胃切除术在诱导显著体重减轻方面发挥重要作用,并且体重减轻可维持至少 10 年。先前的研究支持垂直袖状胃切除术在治疗和管理糖尿病亚组患者方面的作用。有研究报道,在长达 8 年的垂直袖状胃切除术后,11%至 76.9%的肥胖个体停止使用糖尿病药物。主要的持续问题包括术前确定糖尿病患者是否适合接受这种减肥手术。了解该手术的操作过程和由此产生的解剖结构对于将垂直袖状胃切除术作为糖尿病的治疗选择非常重要。在术后期间,特定的宏量营养素目标和微量营养素补充剂对于获得成功和更安全的临床结果非常重要。了解潜在的短期和长期并发症对于降低垂直袖状胃切除术的潜在风险非常重要。这包括识别和治疗术后营养缺乏症和紊乱。垂直袖状胃切除术是长期、有组织的治疗肥胖相关糖尿病计划的一部分。当对肥胖的 2 型糖尿病患者进行垂直袖状胃切除术时,这种方法可能会改善患者的预后。

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