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勃起功能障碍严重程度与主动脉僵硬度的关系。

The relationship between the severity of erectile dysfunction and aortic stiffness.

机构信息

Department of Urology, Faculty of Medicine, Giresun University, Giresun, Turkey.

Department of Cardiology, Faculty of Medicine, Giresun University, Giresun, Turkey.

出版信息

Andrologia. 2020 May;52(4):e13544. doi: 10.1111/and.13544. Epub 2020 Feb 18.

Abstract

Aortic stiffness increases in patients with erectile dysfunction (ED) but it is not known whether aortic stiffness affects the degree of ED. In the present study, we aimed to determine whether there is any relationship between aortic stiffness and the severity of ED. Patients with ED were divided into 3 groups according to the International Index of Erectile Function (IIEF) scores. Mild ED was named as group 1, moderate ED as group 2 and severe ED as group 3. The values of fasting blood glucose (FBG), serum lipid values, total testosterone (T. tes), and free testosterone (F tes) were recorded. Aortic stiffness was determined by pulse wave velocity (PWV) and augmentation index (AIX) measurements. The mean or median values of the laboratory parameters among the groups were similar (p > .05). No statistical difference was found between the groups in terms of AIX value (p = .386). Mean PWV values were calculated as 7.26, 8.30 and 8.78 in group 1, group 2 and group 3 respectively. PWV values were significantly different between groups (p < .0001). PWV values were found to be increased with increasing severity of erectile dysfunction.

摘要

勃起功能障碍(ED)患者的主动脉僵硬度增加,但尚不清楚主动脉僵硬度是否会影响 ED 的严重程度。在本研究中,我们旨在确定主动脉僵硬度与 ED 严重程度之间是否存在任何关系。根据国际勃起功能指数(IIEF)评分,将 ED 患者分为 3 组。轻度 ED 命名为组 1,中度 ED 命名为组 2,重度 ED 命名为组 3。记录空腹血糖(FBG)、血脂值、总睾酮(T. tes)和游离睾酮(F tes)的值。通过脉搏波速度(PWV)和增强指数(AIX)测量来确定主动脉僵硬度。各组实验室参数的均值或中位数相似(p>.05)。AIX 值在各组之间无统计学差异(p=0.386)。组 1、组 2 和组 3 的平均 PWV 值分别为 7.26、8.30 和 8.78。组间 PWV 值差异有统计学意义(p<.0001)。随着勃起功能障碍严重程度的增加,PWV 值增加。

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