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心血管-踝血管指数测量在泌尿系统疾病中的可能临床获益。

Possible Clinical Benefits of Cardio-Ankle Vascular Index Measurement in Urological Diseases.

机构信息

Department of Urology, Trabzon Vakfıkebir State Hospital, Trabzon, Turkey.

Department of Cardiology, Ankara City Hospital, Ankara, Turkey.

出版信息

Vasc Health Risk Manag. 2023 Mar 9;19:127-132. doi: 10.2147/VHRM.S384937. eCollection 2023.

Abstract

Many factors are considered to affect vascular physiology. It is known that one of the reasons for many diseases is a pathology at the microvascular level. Therefore, the relationship between endothelial dysfunction and many diseases is currently being investigated. The clinical evaluations of arterial stiffness have made it possible to perform necessary risk assessment regarding cardiovascular diseases. In this way, protective measures can be taken against microvascular pathologies in many organs. In this paper, we present a review of studies investigating the relationship between urological conditions and the cardio-ankle vascular index (CAVI), a marker of arterial stiffness. As with erectile dysfunction, some studies have shown that conditions such as lower urinary tract symptoms, overactive bladder, and chronic kidney disease are also associated with an elevated CAVI. The association of erectile dysfunction and chronic kidney disease with vascular pathologies has been clearly demonstrated. In addition, lower urinary tract symptoms may be the first sign of silent vascular dysfunction. Assessing arterial stiffness with CAVI can help prevent future cardiovascular events in these patients.

摘要

许多因素被认为会影响血管生理学。已知许多疾病的原因之一是微血管水平的病理学。因此,目前正在研究内皮功能障碍与许多疾病之间的关系。动脉僵硬度的临床评估使得对心血管疾病进行必要的风险评估成为可能。通过这种方式,可以针对许多器官的微血管病变采取保护措施。在本文中,我们回顾了研究尿 路 系 统 疾 病 与 动 脉 僵 硬 指 标 (CAVI)之间关系的研究。与勃起功能障碍一样,一些研究表明,下尿路症状、膀胱过度活动症和慢性肾脏病等疾病也与 CAVI 升高有关。勃起功能障碍和慢性肾脏病与血管病变的关联已得到明确证实。此外,下尿路症状可能是血管功能障碍沉默的早期迹象。使用 CAVI 评估动脉僵硬度可以帮助预防这些患者未来发生心血管事件。

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