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在社区获得性腹泻和医院获得性腹泻的发生中,其在粪便和环境样本中的毒力多样性。

Involvement of in the occurrence of community and hospital acquired diarrhea, and its virulence diversity among the stool and the environmental samples.

机构信息

Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran.

Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Int J Environ Health Res. 2022 Jan;32(1):61-71. doi: 10.1080/09603123.2020.1726300. Epub 2020 Feb 19.

Abstract

Transmission of along the food chain could cause gastrointestinal infections. To show this involvement, the prevalence, putative virulence genotype, and antibiotic resistance phenotype of isolates from stool of 1482 patients with community and hospital acquired diarrhea were compared with 87 isolates from the environmental samples. The results showed infection with in 3.4% of the cases, while 57.4% of vegetable samples were contaminated. Significantly higher frequency of (98%), (98%), (98%), and (90%), but lower rate of (39.2%), was detected among the stool isolates. Multi-drug resistance (MDR) phenotype was detected in 25.5% and 4% of the stool and vegetable isolates, respectively. A higher rate of studied virulence genes was detected among the MDR strains non-MDR strains. These results indicate as a causative agent of diarrhea either among the hospitalized patients and those with community-acquired diarrhea.

摘要

食源性传播可能导致胃肠道感染。为了证明这种关联性,比较了来自 1482 例社区获得性和医院获得性腹泻患者粪便和 87 例环境样本中分离的的流行率、假定毒力基因型和抗生素耐药表型。结果显示,感染率为 3.4%,而 57.4%的蔬菜样本受到污染。粪便分离株中显著更高的(98%)、(98%)、(98%)和(90%),但较低的(39.2%)检出率。在粪便和蔬菜分离株中分别检测到多药耐药(MDR)表型的发生率为 25.5%和 4%。在 MDR 菌株中检测到更高比例的研究毒力基因,而非 MDR 菌株。这些结果表明,食源性传播可能是导致住院患者和社区获得性腹泻的原因之一。

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