Higa Darrel H, Crepaz Nicole, McDonald Christina M, Adegbite-Johnson Adebukola, DeLuca Julia B, Kamitani Emiko, Sipe Theresa Ann
Centers for Disease Control and Prevention, Division of HIV/AIDS Prevention, Atlanta, Georgia.
ICF International, Atlanta, Georgia.
AIDS Educ Prev. 2020 Feb;32(1):1-S7. doi: 10.1521/aeap.2020.32.1.1. Epub 2020 Feb 19.
In the United States, men who have sex with men (MSM) are disproportionately affected by HIV. To identify research gaps and inform HIV prevention for MSM, we conducted a scoping review of systematic reviews using CDC's Prevention Research Synthesis database. Eligibility criteria comprised English-language systematic reviews focused on HIV prevention for MSM, published during 1988-2017, and included at least one U.S. primary study. We coded data type, subpopulations, topics, and key findings. To assess study quality, we used the Assessment of Multiple Systematic Reviews (AMSTAR). Among 129 relevant systematic reviews, study quality was high or moderate for 63%. Most common topics were sexual behavior and disease vulnerability. The most frequently mentioned MSM subgroups were HIV-positive, Black or African American, and young. Research gaps include Hispanic/Latino MSM, pre-exposure prophylaxis (PrEP), treatment as prevention, social determinants of health, health disparities, syndemics, and protective factors for sexual health.
在美国，男男性行为者（MSM）受艾滋病毒影响的比例过高。为了确定研究差距并为男男性行为者的艾滋病毒预防工作提供信息，我们使用疾病控制与预防中心的预防研究综合数据库对系统评价进行了范围界定审查。纳入标准包括1988年至2017年期间发表的、以男男性行为者艾滋病毒预防为重点的英文系统评价，且至少包括一项美国的原发性研究。我们对数据类型、亚人群、主题和主要发现进行了编码。为评估研究质量，我们使用了多重系统评价评估（AMSTAR）。在129篇相关系统评价中，63%的研究质量为高或中等。最常见的主题是性行为和疾病易感性。最常被提及的男男性行为者亚组是艾滋病毒阳性者、黑人或非裔美国人以及年轻人。研究差距包括西班牙裔/拉丁裔男男性行为者、暴露前预防（PrEP）、治疗即预防、健康的社会决定因素、健康差距、综合征以及性健康的保护因素。
