Harding J J, van Heyningen R
Nuffield Laboratory of Ophthalmology, University of Oxford.
Br J Ophthalmol. 1988 Nov;72(11):809-14. doi: 10.1136/bjo.72.11.809.
A case-control study of cataract in Oxfordshire explored the risks and benefits associated with a variety of drugs. Steroids including the diuretic spironolactone, nifedipine, heavy smoking, and beer drinking were associated with a raised risk. On the other hand aspirin-like analgesics (paracetamol, ibuprofen, aspirin, etc. appeared to protect against cataract. Cyclopenthiazide appeared to provide a similar protection.
牛津郡一项关于白内障的病例对照研究探讨了多种药物相关的风险和益处。包括利尿剂螺内酯、硝苯地平在内的类固醇、大量吸烟和饮用啤酒与风险升高相关。另一方面,类阿司匹林镇痛药(对乙酰氨基酚、布洛芬、阿司匹林等)似乎可预防白内障。环戊噻嗪似乎也有类似的预防作用。