Comparison of the antihypertensive effects of indapamide and cyclopenthiazide.

The antihypertensive effects of indapamide, 2.5 mg, and cyclopenthiazide, 0.5 mg daily were compared over a two week period. The falls in both diastolic and systolic blood pressure were greater with indapamide than with cyclopenthiazide reaching statistical significance for the supine diastolic values. This difference was still seen when matching patient groups of similar age, sex or severity of blood pressure were compared.