急性冠状动脉综合征与巴基斯坦农村妇女使用生物质燃料：一项病例对照研究。
Acute coronary syndrome and use of biomass fuel among women in rural Pakistan: a case-control study.
机构信息
Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Department of Community Medicine, People's University of Medical and Health Sciences for Women, Nawabshah, Sindh, Pakistan.
出版信息
Int J Public Health. 2020 Mar;65(2):149-157. doi: 10.1007/s00038-020-01339-w. Epub 2020 Feb 19.
OBJECTIVES
Three billion people use biomass fuel for cooking and heating globally. We assessed the association between acute coronary syndromes (ACS) and use of biomass fuel for cooking.
METHODS
We conducted a case-control study among women living in defined areas that were served by two tertiary care hospitals. A total of 364 women admitted to cardiac care units with ACS were compared with 727 controls, individually matched for age, who were inpatients at the same hospitals with a miscellany of diagnoses. Exposure to biomass fuel and other risk factors was ascertained through a questionnaire and assessed by conditional logistic regression.
RESULTS
After adjustment, risk of ACS was elevated in women who had ever used biomass for cooking. In comparison with never users, the odds ratio for those who currently cooked with biomass was 4.8 (95% confidence interval 1.7, 13.8). However, among those who had ever used biomass, there was no decline in risk with time since last exposure.
CONCLUSIONS
The study found increased risk of ACS from use of biomass for cooking. However, full benefits from interventions may not accrue in short term.
目的
全球有 30 亿人使用生物质燃料做饭和取暖。我们评估了急性冠状动脉综合征（ACS）与烹饪用生物质燃料使用之间的关联。
方法
我们在由两家三级保健医院服务的特定区域内开展了一项病例对照研究。将 364 名因 ACS 入住心脏护理病房的女性与 727 名年龄匹配的、因各种诊断入住同一医院的住院患者作为对照。通过问卷调查确定暴露于生物质燃料和其他危险因素，并通过条件逻辑回归进行评估。
结果
调整后，曾使用生物质燃料做饭的女性发生 ACS 的风险增加。与从不使用者相比，目前使用生物质燃料做饭的女性的比值比为 4.8（95%置信区间 1.7，13.8）。然而，在曾经使用过生物质燃料的人群中，末次暴露后的风险并没有随时间降低。
结论
该研究发现使用生物质燃料做饭会增加 ACS 的风险。然而，短期干预可能不会完全受益。
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