Servei d'Avaluació i Mètodes d'Intervenció (SAMI), Agència de Salut Pública de Barcelona (ASPB), Barcelona, Catalonia, Spain.
CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Support Care Cancer. 2020 Nov;28(11):5213-5221. doi: 10.1007/s00520-020-05337-9. Epub 2020 Feb 20.
Cancer-related fatigue (CRF) is one of the most prolonged discomforts suffered by people who have had cancer. Seventy-eight to ninety-six percent of cancer patients experience fatigue, especially while undergoing treatment. CRF is related to insomnia, anxiety, depression, and also varies depending on age. However, little is known about the factors contributing to CRF and better understanding of determinants of CRF makes it easier to identify early patients at risk and in designing intervention planning. The aim of this study was to assess the influence of precipitating factors (diagnosis of breast cancer and other clinical aspects) and perpetuating factors (social network, quality of life, mental disorders) on the presence of chronic fatigue in women from our cultural context, by social class each other determinants.
It was carried out a mixed cohort study (prospective and retrospective) using a convenience sample of women diagnosed with breast cancer. The information sources were data from the Brief Fatigue Inventory questionnaire and hospital medical records. The dependent variable was fatigue and the independent variables were age, social class, time since diagnoses, cohabitation, comorbidity, relapse, body mass index, mental health (anxiety and depression), social network, social support, and quality of life.
Seventy-two percent of the women in the DAMA cohort reported moderate to severe fatigue. Risk of suffering from severe fatigue was greatest among individuals with low social class, those aged under 50 years, those with chronic disorders who had relapsed, and those with symptoms of anxiety and depression. In our study, CRF did not appear to be related to the stage of the cancer at diagnosis, or to the time since diagnosis.
CRF is an element that the professionals responsible for the control and monitoring of women should take into account as another element to be taken into consideration.
癌症相关疲劳（CRF）是癌症患者最持久的不适之一。78%至 96%的癌症患者会经历疲劳，尤其是在接受治疗期间。CRF 与失眠、焦虑、抑郁有关，并且还因年龄而异。然而，人们对导致 CRF 的因素知之甚少，更好地了解 CRF 的决定因素可以更容易地识别早期有风险的患者，并为干预计划的设计提供依据。本研究的目的是评估促成因素（乳腺癌诊断和其他临床方面）和维持因素（社会网络、生活质量、精神障碍）对我们文化背景下女性慢性疲劳的影响，通过社会阶层来确定彼此的决定因素。
采用方便样本对确诊为乳腺癌的女性进行了混合队列研究（前瞻性和回顾性）。信息来源是简短疲劳量表问卷和医院病历中的数据。因变量是疲劳，自变量是年龄、社会阶层、诊断后时间、同居、合并症、复发、体重指数、心理健康（焦虑和抑郁）、社会网络、社会支持和生活质量。
DAMA 队列中有 72%的女性报告有中度至重度疲劳。低社会阶层、年龄在 50 岁以下、患有慢性疾病且已复发、有焦虑和抑郁症状的个体，患严重疲劳的风险最大。在我们的研究中，CRF 似乎与诊断时的癌症分期或诊断后时间无关。
CRF 是负责控制和监测女性的专业人员应考虑的另一个因素。
