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田原惣清:关于他为现代心脏电生理学理解提供基础所经历磨难的进一步思考。

Sunao Tawara : further musings on his tribulations in providing the basis for the modern-day understanding of cardiac electrophysiology.

作者信息

De Almeida Marcos C, Sanchez-Quintana Damian, Anderson Robert H

机构信息

Department of Genetics and Morphology, Brasilia's University, Campus Asa Norte, Brasília, Cep: 70910-900, Brazil.

Department of Human Anatomy and Cell Biology, Faculty of Medicine, University of Extremadura, Badajoz, Spain.

出版信息

Anat Sci Int. 2020 Jun;95(3):381-386. doi: 10.1007/s12565-020-00530-6. Epub 2020 Feb 20.

DOI:10.1007/s12565-020-00530-6
PMID:32078150
Abstract

Sunao Tawara, who was born in 1873 and died in 1952, is considered the father of modern cardiac electrophysiology. He published his monumental monograph describing the atrioventricular conduction axis in 1906. He achieved this task in the face of multiple tribulations as a doctoral student working in a cultural environment that was not his own. Although his letters underscoring the publication of the monograph have been published, little emphasis has been placed on the potential problems he encountered in bringing his task to fruition. For example, it was not until the final 6 months of his studies that he resolved the issue of the connection between the atrioventricular bundle and the so called "Purkinje cardiomyocytes". His exchanges with his mentor, Ludwig Aschoff, emphasized that the difficulties he encountered in making the connection caused him quite some turmoil. We believe that this issue, and others that he identified in his correspondence, are worthy of further attention.

摘要

田原直尾生于1873年,卒于1952年,被认为是现代心脏电生理学之父。他在1906年发表了描述房室传导轴的不朽专著。作为一名在并非自己文化环境中的博士生,他在面对诸多磨难的情况下完成了这项任务。尽管他强调专著出版的信件已经发表,但很少有人关注他在完成任务过程中可能遇到的问题。例如,直到他研究的最后6个月,他才解决了房室束与所谓“浦肯野心肌细胞”之间的连接问题。他与导师路德维希·阿绍夫的交流强调,他在建立这种连接时遇到的困难给他带来了相当大的困扰。我们认为,这个问题以及他在信件中提到的其他问题值得进一步关注。

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