驾驶模拟中瞳孔反应作为乳腺癌幸存者认知负荷测量指标的初步可行性研究。
Pilot Feasibility Study Examining Pupillary Response During Driving Simulation as a Measure of Cognitive Load in Breast Cancer Survivors.
机构信息
University of Kansas.
University of Maryland.
出版信息
Oncol Nurs Forum. 2020 Mar 1;47(2):203-212. doi: 10.1188/20.ONF.203-212.
OBJECTIVES
To test the feasibility of adding driving simulation tasks to measure visuospatial ability and processing speed to an existing neurocognitive battery for breast cancer survivors (BCSs).
SAMPLE & SETTING: 38 BCSs and 17 healthy controls from a cross-sectional pilot study conducted at the University of Kansas Medical Center.
METHODS & VARIABLES: Exploratory substudy measuring pupillary response, visuospatial ability, and processing speed during two 10-minute driving simulations (with or without n-back testing) in a sample of BCSs with self-reported cognitive complaints and healthy controls.
RESULTS
Feasibility of measurement of pupillary response during driving simulation was demonstrated. No between-group differences were noted for pupillary response during driving simulation. BCSs had greater visuospatial ability and processing speed performance difficulties than healthy controls during driving simulation without n-back testing and slower n-back response time.
IMPLICATIONS FOR NURSING
Preliminary evidence showed a possible link between cancer/treatment on visuospatial ability and processing speed in BCSs.
目的
测试在现有的乳腺癌幸存者（BCS）神经认知测试组合中增加驾驶模拟任务以测量视空间能力和处理速度的可行性。
样本和设置
堪萨斯大学医学中心进行的一项横断面试点研究中的 38 名 BCS 和 17 名健康对照者。
方法和变量
探索性亚研究在报告有认知问题的 BCS 样本和健康对照者中，使用两个 10 分钟的驾驶模拟（带或不带 n-back 测试）测量瞳孔反应、视空间能力和处理速度。
结果
在驾驶模拟期间测量瞳孔反应的可行性得到了验证。在驾驶模拟期间，两组之间的瞳孔反应没有差异。在没有 n-back 测试的驾驶模拟中，BCS 的视空间能力和处理速度表现困难比健康对照组更大，而 n-back 反应时间更慢。
对护理的启示
初步证据表明，癌症/治疗与 BCS 的视空间能力和处理速度之间可能存在联系。
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