Liang Hui, Xu Lingli, Tian Xu, Wang Shuya, Liu Xiaoling, Dai Yi, Kang Li, Chen Lisai, Jin Lifen, Li Qin, Chen Weiqing
Department of Nursing, the First People's Hospital of Yunnan Province.
The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan.
Medicine (Baltimore). 2020 Feb;99(8):e19229. doi: 10.1097/MD.0000000000019229.
The aim of this meta-analysis is to investigate the comparative efficacy between supervised- and home-based programs in patients with ankylosing spondylitis (AS).
A systematic search in PubMed, Web of Science, EMBASE, and the Cochrane Library was electronically performed by 2 independent investigators in order to capture all potential studies comparing supervised- with home-based in patients with AS from inception to April 2018. After extracted essential information, apprised risk of bias, statistical analysis was performed with Review Manager (RevMan) software (version 5.3.0). The protocol was registered at PROSPERO platform with an identifier of CRD42018097046.
A total of 7 studies comprising 271 patients were included finally. Meta-analyses showed that, compared to home-based program, supervised-based program was associated with reduced bath ankylosing spondylitis metrology index (BASMI) scores (mean difference [MD], -0.45; 95% confidence interval [CI], -0.73, -0.17), bath ankylosing spondylitis disease activity index (BASDAI) scores (MD, -0.48; 95% CI, -0.88, -0.08), and bath ankylosing spondylitis functional index (BASFI) scores (MD, -0.78; 95% CI, -1.19, -0.37). However, depression scores (standard mean difference, -0.22; 95% CI, -0.58, 0.14) between the 2 groups showed no significant defference.
Both supervised- and home-based programs can benefit to reduce BASMI, BASDAI, and BASFI scores in AS patients. However, short-term, supervised exercise program may be more effective than home-based exercises at decreasing disease activity with AS.
本荟萃分析旨在研究强直性脊柱炎（AS）患者中监督式项目与家庭式项目的疗效比较。
由2名独立研究人员在PubMed、科学网、EMBASE和Cochrane图书馆进行系统检索，以获取从开始到2018年4月所有比较AS患者监督式项目与家庭式项目的潜在研究。提取基本信息、评估偏倚风险后，使用Review Manager（RevMan）软件（5.3.0版）进行统计分析。该方案已在PROSPERO平台注册，标识符为CRD42018097046。
最终纳入7项研究，共271例患者。荟萃分析表明，与家庭式项目相比，监督式项目与强直性脊柱炎浴盆计量指数（BASMI）评分降低相关（平均差[MD]，-0.45；95%置信区间[CI]，-0.73，-0.17），强直性脊柱炎浴盆疾病活动指数（BASDAI）评分降低（MD，-0.48；95%CI，-0.88，-0.08），以及强直性脊柱炎浴盆功能指数（BASFI）评分降低（MD，-0.78；95%CI，-1.19，-0.37）。然而，两组之间的抑郁评分（标准平均差，-0.22；95%CI，-0.58，0.14）无显著差异。
监督式项目和家庭式项目均有助于降低AS患者的BASMI、BASDAI和BASFI评分。然而，短期的监督式运动项目在降低AS疾病活动度方面可能比家庭式运动更有效。
