Department of Endocrinology, Sheri-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India.
Department of General Medicine, Government Medical College, Srinagar, Jammu & Kashmir, India.
Int J Gynaecol Obstet. 2020 May;149(2):231-236. doi: 10.1002/ijgo.13125. Epub 2020 Mar 20.
To estimate the prevalence of polycystic ovary syndrome (PCOS) among women of reproductive age across educational institutions in the Kashmir valley.
A cross-sectional study was conducted from May 2013 to May 2015. Eligible girls and women aged 15-40 years were included using a multistage random selection process from five out of 12 districts in turn housing 14 educational institutions. They were screened through a brief questionnaire in a staged manner. After obtaining consent, women underwent detailed clinical, biochemical, hormonal, and sonographic evaluation to satisfy Rotterdam 2003 criteria. The participants were also evaluated using NIH and AE-PCOS criteria.
Out of a total of 3300 eligible women, 964 women were evaluated using a structured questionnaire. Among these, 446 (46.4%) were identified as "probable PCOS" cases. Out of 171 probable PCOS women who completed all biochemical, hormonal, and sonographic assessment, 35.3% qualified for a diagnosis of PCOS using Rotterdam criteria. The prevalence of PCOS was 28.9% by NIH criteria and 34.3% by AE-PCOS criteria.
The prevalence of PCOS is high among Kashmiri women and is probably the highest in a published series globally. A countrywide systematic prevalence study is warranted to reconfirm the findings.
评估克什米尔谷各教育机构育龄妇女多囊卵巢综合征(PCOS)的流行率。
本横断面研究于 2013 年 5 月至 2015 年 5 月进行。采用多阶段随机抽样方法,从 12 个区中依次选择 5 个区的 14 所教育机构,纳入年龄在 15-40 岁之间的合格女孩和妇女。通过分阶段的简要问卷对她们进行筛选。在获得同意后,对妇女进行详细的临床、生化、激素和超声评估,以满足 2003 年鹿特丹标准。还使用 NIH 和 AE-PCOS 标准对参与者进行评估。
在总共 3300 名合格妇女中,964 名妇女使用结构化问卷进行了评估。其中,446 名(46.4%)被确定为“可能的 PCOS”病例。在 171 名完成所有生化、激素和超声评估的可能 PCOS 妇女中,35.3%符合 Rotterdam 标准的 PCOS 诊断。根据 NIH 标准,PCOS 的患病率为 28.9%,根据 AE-PCOS 标准,患病率为 34.3%。
克什米尔妇女的 PCOS 患病率较高,可能是全球已发表系列中最高的。需要进行全国范围内的系统患病率研究来证实这些发现。