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短期低压缺氧在预防大鼠在声音应激期间脑循环紊乱中的作用。

The role of short-term hypobaric hypoxia in prevention of disorders of the cerebral circulation in rats during acoustic stress.

作者信息

Ryasina T V, Koshelev V B, Krushinsky A L, Lozhnikova S M, Sotskaya M N, Lyudkovskaya I G

机构信息

Research Institute of Neurology of the U.S.S.R., Academy of Medical Sciences, Moscow.

出版信息

Brain Res. 1988 Nov 8;473(1):153-6. doi: 10.1016/0006-8993(88)90327-7.

DOI:10.1016/0006-8993(88)90327-7
PMID:3208118
Abstract

The 2 h influence of the 'altitude' of 5000 m on the genetically epilepsy-prone rats of the KM line reduces the death rate and the extent of neurological changes (the frequency and severity of motion disorders and the development of intracranial haemorrhages) under the conditions of acoustic stress.

摘要

5000米“海拔”对KM系遗传性癫痫易感大鼠的两小时影响降低了在声学应激条件下的死亡率和神经学变化程度(运动障碍的频率和严重程度以及颅内出血的发生情况)。

相似文献

1
The role of short-term hypobaric hypoxia in prevention of disorders of the cerebral circulation in rats during acoustic stress.短期低压缺氧在预防大鼠在声音应激期间脑循环紊乱中的作用。
Brain Res. 1988 Nov 8;473(1):153-6. doi: 10.1016/0006-8993(88)90327-7.
2
[Effect of short-term adaptation to hypoxia on the development of acute cerebral circulatory disorders in rats genetically disposed to epilepsy].[短期低氧适应对遗传性癫痫倾向大鼠急性脑循环障碍发展的影响]
Biull Eksp Biol Med. 1987 Mar;103(3):373-6.
3
[The protective action of different types and regimens of adaptation to hypoxia on the development of stress-induced lesions in KM strain (Krushinskiĭ-Molodkina) rats].[不同类型和方案的低氧适应对KM品系(克鲁申斯基-莫洛迪纳)大鼠应激性损伤发展的保护作用]
Fiziol Zh SSSR Im I M Sechenova. 1989 Nov;75(11):1576-84.
4
[Antistress and angioprotective influence of nitric oxide in epilepsy-prone rats of Krushinskiĭ-Molodkina strain].[一氧化氮对克鲁申斯基-莫洛迪纳品系癫痫易感大鼠的抗应激和血管保护作用]
Ross Fiziol Zh Im I M Sechenova. 2005 Jan;91(1):89-96.
5
[Adaptation to periodic hypoxia restricts subdural hemorrhages in audiogenic epileptiform convulsions in rats].[适应周期性低氧可限制大鼠听源性癫痫样惊厥中的硬膜下出血]
Biull Eksp Biol Med. 1993 Dec;116(12):572-4.
6
[Changes in reactivity of the middle cerebral artery caused by cerebral circulation disturbances of ischemic and hemorrhagic types in rats].[大鼠缺血性和出血性类型脑循环障碍引起的大脑中动脉反应性变化]
Ross Fiziol Zh Im I M Sechenova. 1998 Jul;84(7):672-8.
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[Differences in the development of the phenomenon of the adaptive stabilization of the DNA in myocardial nuclei during adaptation to stress and altitude hypoxia: the role of heat shock proteins].[应激与高原低氧适应过程中心肌细胞核DNA适应性稳定现象发展的差异:热休克蛋白的作用]
Dokl Akad Nauk SSSR. 1991;317(6):1503-6.
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[Effects of adaptation to stress exposure and periodic hypoxia on bioelectric activity of cardiomyocytes of isolated heart in ischemia and reperfusion].
Biull Eksp Biol Med. 1991 Dec;112(12):573-5.
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[Adaptation to high altitude hypoxia facilitates a limitation of lipid peroxidation activation in inflammation and stress].[对高原缺氧的适应有助于限制炎症和应激中脂质过氧化的激活]
Biull Eksp Biol Med. 1995 Jun;119(6):590-3.
10
[Adaptation of the body to stress and to altitude hypoxia leads to accumulation of various isoforms of hsp 70 in the myocardium].
Dokl Akad Nauk SSSR. 1991;320(2):470-2.

引用本文的文献

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Hypoxic preconditioning: a novel intrinsic cytoprotective strategy.缺氧预处理:一种新型的内源性细胞保护策略。
Mol Neurobiol. 2005;31(1-3):255-71. doi: 10.1385/MN:31:1-3:255.
2
Carnosine: an endogenous neuroprotector in the ischemic brain.肌肽:缺血性脑内的内源性神经保护剂。
Cell Mol Neurobiol. 1999 Feb;19(1):45-56. doi: 10.1023/a:1006960407008.
3
Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals.肌肽是一种内源性自由基神经保护剂的生化和生理学证据。
Cell Mol Neurobiol. 1997 Apr;17(2):259-71. doi: 10.1023/a:1026374114314.