Tong Jiankun, Jadallah Sana, Rodgers William H, Jung Gabriel, Fulman Malvina, Swaika Abhisek
Department of Pathology, New York-Presbyterian Queens, 56-45 Main Street, Flushing, NY 11355, USA.
Weill Cornell Medical College, 525 East 68th Street, Box 130, New York, NY 10065, USA.
Case Rep Hematol. 2020 Jan 19;2020:6124325. doi: 10.1155/2020/6124325. eCollection 2020.
Primary effusion lymphoma (PEL) is a rare and very aggressive large B-cell lymphoma usually presenting as serous effusions without a tumor mass. It is universally associated with human herpesvirus type-8 (HHV-8) infection. It most commonly occurs in the body cavities and rarely develops as solid tumor masses in the wall of cavity and other organs, and it has been termed as extracavitary PEL. Extracavitary PEL has been reported in the lymph nodes and extranodal sites. Here we report a rare case of extracavitary PEL occurring in the bladder and ureter of a human immunodeficiency virus (HIV)-negative 76-year-old Chinese male, presenting with right leg swelling, erythema, and pain. To the best of our knowledge, this is the first case of extracavitary PEL presenting in the bladder and ureter.
原发性渗出性淋巴瘤（PEL）是一种罕见且侵袭性很强的大B细胞淋巴瘤，通常表现为浆液性渗出液，无肿瘤肿块。它普遍与人类疱疹病毒8型（HHV-8）感染有关。它最常发生于体腔，很少在腔壁和其他器官发展为实体肿瘤肿块，这种情况被称为腔外PEL。腔外PEL已在淋巴结和结外部位有报道。在此，我们报告一例罕见的腔外PEL病例，发生在一名76岁HIV阴性的中国男性的膀胱和输尿管，表现为右腿肿胀、红斑和疼痛。据我们所知，这是首例发生在膀胱和输尿管的腔外PEL病例。
