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一项支持其医学相关性的循证数据的系统评价。

: A Systematic Review of Evidence-Based Data in support of Its Medicinal Relevance.

作者信息

Boison Daniel, Adinortey Cynthia Ayefoumi, Babanyinah Godwin Kweku, Quasie Olga, Agbeko Rosemary, Wiabo-Asabil Gilbert Kofi, Adinortey Michael Buenor

机构信息

Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.

Department of Molecular Biology and Biotechnology, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.

出版信息

Scientifica (Cairo). 2019 Dec 25;2019:3732687. doi: 10.1155/2019/3732687. eCollection 2019.

DOI:10.1155/2019/3732687
PMID:32082693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7011497/
Abstract

() is a plant commonly known as ginger lily, spiral ginger, or bush cane. It is reportedly used in traditional medicine practice (TMP) to treat and manage many ailments including diabetes mellitus, stomach ache, arthritis, inflammation, and gout. These purported ethnomedicinal uses have triggered many research studies on the plant to amass scientific evidence. However, these research reports are scattered, and thus, this systematic review seeks to provide a comprehensive update on it covering its traditional uses, phytochemical and nutritional constituents, pharmacological activities, and toxicological effects. An online search was done using search engines such as Google Scholar, PubMed, and ScienceDirect from the period 1970 to 2019. The online search included the use of keywords, " Ker-Gawl" or "." The search revealed that the stem and leaves of the plant contain substantial amounts of micronutrients and macronutrients. The leaves, stem, rhizomes, and roots of contain several steroidal sapogenins, aferosides, dioscin, and paryphyllin C and flavonoid glycoside kaempferol-3-O--L-rhamnopyranoside. Experimental studies on various parts of the plant showed bioactivities such as antihyperglycemic, hepatocellular protection, cardioprotection, nephroprotection, testicular protection, CNS depressant, analgesic, antiarthritis, antibacterial, and antioxidant. Based on these evident data, it is concluded that the plant could be used as an alternative and complementary therapy for many oxidative stress-related diseases, provided further scientific studies on the toxicological and pharmacological aspects are carried out.

摘要

()是一种通常被称为姜花、螺旋姜或丛林甘蔗的植物。据报道,它在传统医学实践中用于治疗和管理多种疾病,包括糖尿病、胃痛、关节炎、炎症和痛风。这些所谓的民族药用用途引发了许多关于该植物的研究,以积累科学证据。然而,这些研究报告较为分散,因此,本系统综述旨在提供关于它的全面更新,涵盖其传统用途、植物化学和营养成分、药理活性以及毒理学效应。使用谷歌学术、PubMed和ScienceDirect等搜索引擎在1970年至2019年期间进行了在线搜索。在线搜索包括使用关键词“Ker - Gawl”或“.”。搜索结果显示,该植物的茎和叶含有大量的微量营养素和常量营养素。()的叶、茎、根茎和根含有几种甾体皂苷元、阿费罗苷、薯蓣皂苷和帕里菲林C以及黄酮苷山柰酚 - 3 - O - β - L - 鼠李吡喃糖苷。对该植物各个部位的实验研究显示出抗高血糖、肝细胞保护、心脏保护、肾脏保护、睾丸保护、中枢神经系统抑制、镇痛、抗关节炎、抗菌和抗氧化等生物活性。基于这些明显的数据,可以得出结论,该植物可作为许多与氧化应激相关疾病的替代和补充疗法,但前提是要对其毒理学和药理学方面进行进一步的科学研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/baee6bfa9db3/SCIENTIFICA2019-3732687.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/042742753dd2/SCIENTIFICA2019-3732687.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/3a3fd28f2031/SCIENTIFICA2019-3732687.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/baee6bfa9db3/SCIENTIFICA2019-3732687.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/042742753dd2/SCIENTIFICA2019-3732687.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/3a3fd28f2031/SCIENTIFICA2019-3732687.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca57/7011497/baee6bfa9db3/SCIENTIFICA2019-3732687.003.jpg

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