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心力衰竭患者慢性疼痛的药物治疗综述

A Review of the Pharmacological Management of Chronic Pain in Patients with Heart Failure.

作者信息

Majeed Muhammad Hassan, Ali Ali Ahsan, Khalil Hafiza Ayesha, Bacon Douglas, Imran Hafiz Muhammad

机构信息

Dr. Majeed is with the Department of Anesthesiology and Critical Care Management, Johns Hopkins Hospital in Baltimore, Maryland.

Dr. Ali is with the Department of Psychiatry, Icahn School of Medicine at Mount Sinai (Elmhurst) in Queens, New York.

出版信息

Innov Clin Neurosci. 2019 Nov 1;16(11-12):25-27.

Abstract

The incidence rates of heart failure (HF) and chronic pain increase with age. In the geriatric population, both disorders often coexist and pose a challenge to clinicians in treating them simultaneously. We conducted an online literature search for reports of the heart failure effects of pharmacological treatments for chronic pain. Topical pain medications are favored agents because of their efficacy, tolerability, and favorable side-effect profile. Acetaminophen is a preferred oral medication for the treatment of pain in patients with HF. Due to deleterious effects including HF, the long-term use of oral nonsteroidal anti-inflammatory drugs and gabapentinoids are discouraged. Prescribers should thoroughly consider the risk-benefit ratio and individual patient-risk profile before instituting pharmacological treatment for chronic pain in patients with HF.

摘要

心力衰竭(HF)和慢性疼痛的发病率随年龄增长而增加。在老年人群中,这两种疾病常常并存,给临床医生同时治疗它们带来挑战。我们进行了一项在线文献检索,以查找关于慢性疼痛药物治疗对心力衰竭影响的报告。局部用止痛药因其疗效、耐受性和良好的副作用特征而受到青睐。对乙酰氨基酚是治疗心力衰竭患者疼痛的首选口服药物。由于包括心力衰竭在内的有害影响,不鼓励长期使用口服非甾体抗炎药和加巴喷丁类药物。在对心力衰竭患者进行慢性疼痛的药物治疗之前,开处方者应充分考虑风险效益比和个体患者的风险状况。

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本文引用的文献

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Mindfulness-based interventions for chronic pain: Evidence and applications.正念干预慢性疼痛:证据与应用。
Asian J Psychiatr. 2018 Feb;32:79-83. doi: 10.1016/j.ajp.2017.11.025. Epub 2017 Dec 5.
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Pregabalin and heart failure: A population-based study.普瑞巴林与心力衰竭:一项基于人群的研究。
Pharmacoepidemiol Drug Saf. 2017 Sep;26(9):1087-1092. doi: 10.1002/pds.4239. Epub 2017 Jun 16.
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Topical capsaicin for pain in osteoarthritis: A literature review.外用辣椒素治疗骨关节炎疼痛:文献综述。
Reumatol Clin (Engl Ed). 2018 Jan-Feb;14(1):40-45. doi: 10.1016/j.reuma.2016.07.008. Epub 2016 Aug 27.
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A meta-analysis of proinflammatory cytokines in chronic heart failure.慢性心力衰竭中促炎细胞因子的荟萃分析。
Heart Asia. 2014 Sep 6;6(1):130-6. doi: 10.1136/heartasia-2013-010484. eCollection 2014.

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