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多任务分组双向长短期记忆网络在心电图分类中的应用

A Multi-Task Group Bi-LSTM Networks Application on Electrocardiogram Classification.

作者信息

Lv Qiu-Jie, Chen Hsin-Yi, Zhong Wei-Bin, Wang Ying-Ying, Song Jing-Yan, Guo Sai-Di, Qi Lian-Xin, Chen Calvin Yu-Chian

机构信息

1Artificial Intelligence Medical Center, School of Intelligent Systems EngineeringSun Yat-sen UniversityShenzhen510275China.

2School of Software and Applied TechnologyZhengzhou UniversityZhengzhou450002China.

出版信息

IEEE J Transl Eng Health Med. 2019 Nov 12;8:1900111. doi: 10.1109/JTEHM.2019.2952610. eCollection 2020.

Abstract

BACKGROUND

Cardiovascular diseases (CVD) are the leading cause of death globally. Electrocardiogram (ECG) analysis can provide thoroughly assessment for different CVDs efficiently. We propose a multi-task group bidirectional long short-term memory (MTGBi-LSTM) framework to intelligent recognize multiple CVDs based on multi-lead ECG signals.

METHODS

This model employs a Group Bi-LSTM (GBi-LSTM) and Residual Group Convolutional Neural Network (Res-GCNN) to learn the dual feature representation of ECG space and time series. GBi-LSTM is divided into Global Bi-LSTM and Intra-Group Bi-LSTM, which can learn the features of each ECG lead and the relationship between leads. Then, through attention mechanism, the different lead information of ECG is integrated to make the model to possess the powerful feature discriminability. Through multi-task learning, the model can fully mine the association information between diseases and obtain more accurate diagnostic results. In addition, we propose a dynamic weighted loss function to better quantify the loss to overcome the imbalance between classes.

RESULTS

Based on more than 170,000 clinical 12-lead ECG analysis, the MTGBi-LSTM method achieved accuracy, precision, recall and F1 of 88.86%, 90.67%, 94.19% and 92.39%, respectively. The experimental results show that the proposed MTGBi-LSTM method can reliably realize ECG analysis and provide an effective tool for computer-aided diagnosis of CVD.

摘要

背景

心血管疾病(CVD)是全球主要的死亡原因。心电图(ECG)分析可以有效地为不同的心血管疾病提供全面评估。我们提出了一种多任务组双向长短期记忆(MTGBi-LSTM)框架,以基于多导联心电图信号智能识别多种心血管疾病。

方法

该模型采用组双向长短期记忆(GBi-LSTM)和残差组卷积神经网络(Res-GCNN)来学习心电图空间和时间序列的双重特征表示。GBi-LSTM分为全局双向长短期记忆(Global Bi-LSTM)和组内双向长短期记忆(Intra-Group Bi-LSTM),可以学习每个心电图导联的特征以及导联之间的关系。然后,通过注意力机制,整合心电图的不同导联信息,使模型具有强大的特征判别能力。通过多任务学习,模型可以充分挖掘疾病之间的关联信息,获得更准确的诊断结果。此外,我们提出了一种动态加权损失函数,以更好地量化损失,克服类间不平衡。

结果

基于超过170,000例临床12导联心电图分析,MTGBi-LSTM方法的准确率、精确率、召回率和F1值分别达到88.86%、90.67%、94.19%和92.39%。实验结果表明,所提出的MTGBi-LSTM方法能够可靠地实现心电图分析,为心血管疾病的计算机辅助诊断提供了一种有效的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c087/7028438/895a250f22bf/chen1-2952610.jpg

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