Gupta Mrinal, Lotti Torello, Goldust Mohamad
Treatwell Skin Centre, Jammu, India.
Department of Dermatology, University of Studies Guglielmo Marconi, Rome, Italy.
Dermatol Ther. 2020 May;33(3):e13280. doi: 10.1111/dth.13280. Epub 2020 Feb 28.
Isotretinoin is a safe and useful medication for acne management. Adverse effects are mostly related to cutaneous and mucous membranes. We present a case of a 24-year-old female patient who was on treatment with isotretinoin for acne vulgaris Grade 4. After 6 months of treatment, the patient presented with localized patch of hair loss. Beginning of alopecia areata in patients with acne vulgaris could be regarded as a side effect of retinoids due to anti-acne therapy. The exact mechanism by which retinoids cause hair loss is not known.
异维A酸是治疗痤疮的一种安全有效的药物。不良反应大多与皮肤和黏膜有关。我们报告一例24岁女性患者，她正在接受异维A酸治疗重度寻常痤疮。治疗6个月后，患者出现局部脱发斑。寻常痤疮患者斑秃的发生可被视为抗痤疮治疗中维甲酸类药物的一种副作用。维甲酸类药物导致脱发的确切机制尚不清楚。
