Neumann Ariane, Brogden Graham, von Köckritz-Blickwede Maren
Department of Clinical Sciences, Division of Infection Medicine, Lund University, Baravägen 27, 22184 Lund, Sweden.
Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Buenteweg 17, 30559 Hannover, Germany.
Biology (Basel). 2020 Feb 18;9(2):34. doi: 10.3390/biology9020034.
The discovery, in 2004, of extracellular traps released by neutrophils has extended our understanding of the mode of action of various innate immune cells. This fascinating discovery demonstrated the extracellular trapping and killing of various pathogens by neutrophils. During the last decade, evidence has accumulated showing that extracellular traps play a crucial role in the defence mechanisms of various cell types present in vertebrates, invertebrates, and plants. The aim of this review is to summarise the relevant literature on the evolutionary history of extracellular traps used as a weapon in various kingdoms of life.
2004年，中性粒细胞释放细胞外陷阱的发现扩展了我们对各种先天免疫细胞作用方式的理解。这一引人入胜的发现表明中性粒细胞可在细胞外捕获并杀死各种病原体。在过去十年中，越来越多的证据表明，细胞外陷阱在脊椎动物、无脊椎动物和植物中存在的各种细胞类型的防御机制中发挥着关键作用。这篇综述的目的是总结关于细胞外陷阱作为生命各王国中一种武器的进化史的相关文献。
