Chubinskaia S G, Makogonenko E M, Veksler I G
Eksp Onkol. 1988;10(5):46-9.
The method of fibrin plates and electrophoresis in PAAG was used to study the activity and forms of plasminogen activators (PA) in extracts of normal tissues (muscle, lungs) as well as of the malignant tumours and the lungs of mice during metastatic spreading and under certain drugs (trielin and cyclophosphane). It was stated that determination of the specific activity level of plasminogen activator in a target organ (lungs) may be used as one of the indices during evaluation of the antimetastatic effect.
采用纤维蛋白平板法和聚丙烯酰胺凝胶电泳法，研究正常组织（肌肉、肺）提取物、小鼠恶性肿瘤组织以及发生转移扩散的小鼠肺部组织在某些药物（三乙膦酸铝和环磷酰胺）作用下纤溶酶原激活物（PA）的活性和形式。结果表明，测定靶器官（肺）中纤溶酶原激活物的比活性水平，可作为评估抗转移效果的指标之一。
