Universidade Federal de Pelotas, Programa de Pós-Graduação em Nutrição e Alimentação, Pelotas, RS, Brazil.
Universidade Federal de Pelotas, Programa de Pós-Graduação em Nutrição e Alimentação, Pelotas, RS, Brazil.
J Pediatr (Rio J). 2021 Jan-Feb;97(1):103-108. doi: 10.1016/j.jped.2020.01.003. Epub 2020 Feb 19.
To investigate eating behavior and serum concentration of triglycerides in children and adolescents with autistic spectrum disorder.
Cross-sectional study conducted in the neurodevelopment nucleus, from October 2018 to April 2019 in a neurodevelopment center in the city of Pelotas/RS. Blood samples were collected, and serum was essayed for triglycerides by colorimetric enzymatic reaction. The Children's Eating Behavior Questionnaire was applied to the parents. The comparison between two or three categories of variables was performed with nonparametric tests. Linear regression was used to access the association between the log triglyceride serum concentration and the score above or below the median score of the food response and emotional overeating subscales.
Sixty patients were evaluated. The average age was 8.6±3.2 years and most were white (75 %), male (80 %), and overweight (66%). Half of the sample had elevated triglycerides. Triglyceride concentrations were higher among overweight children and adolescents with higher median scores on the "food response" and "emotional overeating" subscales. In the adjusted analysis, the association between triglycerides and higher scores on subscales reflecting interest in food remained significant.
Children and adolescents with autistic spectrum disorder present high triglyceride concentrations associated with a greater interest in food. Knowledge of this eating behavior may provide more effective nutritional intervention in this population.
研究自闭症谱系障碍儿童和青少年的饮食行为和甘油三酯血清浓度。
这是一项 2018 年 10 月至 2019 年 4 月在佩洛塔斯/RS 市神经发育中心的神经发育核进行的横断面研究。采集血样,并通过比色酶反应测定血清甘油三酯。向家长应用儿童饮食行为问卷。使用非参数检验比较两个或三个类别的变量。使用线性回归来评估血清甘油三酯浓度的对数与食物反应和情绪性暴食分量表的中位数得分以上或以下的得分之间的关联。
共评估了 60 例患者。平均年龄为 8.6±3.2 岁,大多数为白人(75%)、男性(80%)和超重(66%)。一半的样本甘油三酯升高。超重的儿童和青少年的甘油三酯浓度较高,“食物反应”和“情绪性暴食”分量表的中位数得分较高。在调整分析中,甘油三酯与反映对食物兴趣的分量表得分较高之间的关联仍然显著。
自闭症谱系障碍儿童和青少年存在高甘油三酯浓度,与对食物的更大兴趣有关。了解这种饮食行为可能为该人群提供更有效的营养干预。