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微创手术非子宫切除术妇科手术后的加速康复结局。

Enhanced recovery after surgery outcomes in minimally invasive nonhysterectomy gynecologic procedures.

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital of University of Pittsburgh Medical Center, Pittsburgh, PA.

Clinical and Translational Science Institute, Office of Clinical Research, University of Pittsburgh, Pittsburgh, PA.

出版信息

Am J Obstet Gynecol. 2020 Aug;223(2):234.e1-234.e8. doi: 10.1016/j.ajog.2020.02.008. Epub 2020 Feb 20.

Abstract

BACKGROUND

Improved patient outcomes and satisfaction associated with enhanced recovery after surgery protocols have increasingly replaced traditional perioperative anesthesia care. Fast-track surgery pathways have been extensively validated in patients undergoing hysterectomies, yet the impact on fertility-sparing laparoscopic gynecologic operations, particularly those addressing chronic pain conditions, has not been examined.

OBJECTIVE

The objective of the study was to determine the effects of enhanced recovery after surgery pathway implementation compared with conventional perioperative care in women undergoing laparoscopic minimally invasive nonhysterectomy gynecologic procedures.

STUDY DESIGN

We conducted a retrospective cohort study of women undergoing uterine-sparing laparoscopic gynecologic procedures for benign conditions (tubal/adnexal pathology, endometriosis, or leiomyomas) during a 24 month period before and after enhanced recovery after surgery implementation at a tertiary care center. We compared immediate perioperative outcomes and 30 day complications. The primary outcome was same-day discharge rates. Factors influencing unplanned admissions, postoperative pain, sedation, nausea, and vomiting represented secondary analyses.

RESULTS

A total of 410 women (enhanced recovery after surgery, n = 196; conventional perioperative care, n = 214) met inclusion criteria. Following enhanced recovery after surgery implementation, same-day discharge rates increased by 9.4% (P = .001). Reductions in postoperative pain and nausea/vomiting represented the primary driving factor behind lower unplanned admissions. Higher preoperative antiemetic medication administration in the enhanced recovery after surgery group resulted in a 57% reduction in postanesthesia care unit antiemetics (P < .001). Total perioperative narcotic medication use was also significantly reduced by 64% (P < .001), and the enhanced recovery after surgery cohort still demonstrated significantly lower postanesthesia unit care pain scores at hours 2 and 3 (P < .001). A 19 minute shorter postanesthesia care unit stay was noted in the enhanced recovery after surgery cohort (P = .036). Increased same-day discharge did not lead to higher postoperative complications or changes in 30 day emergency department visits or readmissions in patients with enhanced recovery after surgery.

CONCLUSION

Enhanced recovery after surgery implementation resulted in increased same-day discharge rates and improved perioperative outcomes without affecting 30 day morbidity in women undergoing laparoscopic minimally invasive nonhysterectomy gynecologic procedures.

摘要

背景

与传统围手术期麻醉护理相比,术后恢复加速方案与患者结局改善和满意度提高相关,已广泛应用于接受子宫切除术的患者。然而,关于保留生育功能的腹腔镜妇科手术,特别是针对慢性疼痛疾病的手术,其快速康复手术途径的影响尚未得到研究。

目的

本研究旨在确定与传统围手术期护理相比,术后恢复加速方案在接受保留子宫的腹腔镜妇科微创手术的女性中的效果。

研究设计

我们进行了一项回顾性队列研究,纳入了在一家三级保健中心实施术后恢复加速方案前后 24 个月期间,因良性疾病(输卵管/附件病变、子宫内膜异位症或子宫肌瘤)接受保留子宫的腹腔镜妇科手术的女性。我们比较了即刻围手术期结局和 30 天并发症。主要结局是当日出院率。影响非计划入院、术后疼痛、镇静、恶心和呕吐的因素为次要分析。

结果

共有 410 名女性(术后恢复加速组,n=196;传统围手术期护理组,n=214)符合纳入标准。实施术后恢复加速方案后,当日出院率增加了 9.4%(P=0.001)。术后疼痛和恶心/呕吐的减少是导致非计划入院率降低的主要因素。术后恢复加速组术前使用更多止吐药,使麻醉后护理单元止吐药的使用减少了 57%(P<0.001)。围手术期阿片类药物的总使用量也显著减少了 64%(P<0.001),而且术后恢复加速组在 2 小时和 3 小时时的麻醉后护理单元疼痛评分仍显著较低(P<0.001)。术后恢复加速组的麻醉后护理单元停留时间缩短了 19 分钟(P=0.036)。术后恢复加速组患者的当日出院并未导致更高的术后并发症,也未导致 30 天内急诊就诊或再入院率的变化。

结论

实施术后恢复加速方案可提高当日出院率,改善围手术期结局,而不会影响接受保留生育功能的腹腔镜妇科微创手术的女性的 30 天发病率。

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