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印度人群中糖尿病高危个体的睡眠障碍

Sleep Disorders in Individuals With High Risk for Diabetes in Indian Population.

作者信息

Maity Kalyan, Nagarathna Raghuram, Anand Akshay, Patil Suchitra S, Singh Amit, Rajesh S K, Ramesh Latha, Sridhar P, Thakur Uttam Kumar, Nagendra Hongasandra R

机构信息

Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana (S-VYASA), Bengaluru, Karnataka, India.

Department of Neurology, Neuroscience Research Lab, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

出版信息

Ann Neurosci. 2020 Jul;27(3-4):183-189. doi: 10.1177/0972753121998470. Epub 2021 Apr 24.

DOI:10.1177/0972753121998470
PMID:34556958
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8455005/
Abstract

BACKGROUND

Sleep restores physiology and neurochemical components of our body and is essential for physical and mental health. Sleep disorders (SDs) are associated with insulin resistance and metabolic disorders. The association between SDs and diabetes needs to be understood in the Indian population.

PURPOSE

The purpose was to investigate the association between SD and diabetes in the Indian population.

METHODS

As a part of nationwide Niyantrita Madhumeha Bharata Abhiyaan-2017 (NMB-2017), a cross-sectional study was conducted and data was collected from seven zones of India, after screening through the Indian Diabetes Risk Score (IDRS). The sleep quality was assessed on a scale of 1 to 4 (very good = 1, very bad = 4). The time taken to fall asleep (sleep latency) was assessed on a scale of 0 to 5 ("0" = nil and "5" = >1.5 h). Stress was assessed by the perceived stress scale.

RESULTS

Bad sleep quality was positively (odds ratio 1.055, CI [1.001, 1.113], and P < .01) associated with self-reported known diabetes. Increased time taken to fall in sleep (sleep latency) was associated significantly with IDRS high risk (odds ratio 1.085, CI [1.008, 1.168], and P = .01), with an average sleep latency /time takes to fall in sleep (maximum range 5 [>1.5 h], mode 2 [10 to 30 min]) minutes. Moderate stress was significantly associated with bad sleep quality (odds ratio 1.659).

CONCLUSION

A positive association of bad sleep quality and stress with diabetes, and an increased sleep latency in the IDRS high-risk population point to the role of modifiable risk factors. Behavioral modification and stress reduction by using yoga may be beneficial in the better management of diabetes.

摘要

背景

睡眠可恢复我们身体的生理和神经化学组成部分,对身心健康至关重要。睡眠障碍(SDs)与胰岛素抵抗和代谢紊乱相关。需要了解印度人群中睡眠障碍与糖尿病之间的关联。

目的

目的是调查印度人群中睡眠障碍与糖尿病之间的关联。

方法

作为全国性的2017年尼扬特里塔·马杜梅哈·巴拉塔行动(NMB - 2017)的一部分,开展了一项横断面研究,在通过印度糖尿病风险评分(IDRS)进行筛查后,从印度的七个地区收集数据。睡眠质量按1至4分进行评估(非常好 = 1分,非常差 = 4分)。入睡时间(睡眠潜伏期)按0至5分进行评估(“0” = 无,“5” = >1.5小时)。压力通过感知压力量表进行评估。

结果

睡眠质量差与自我报告的已知糖尿病呈正相关(比值比1.055,可信区间[1.001, 1.113],P <.01)。入睡时间增加(睡眠潜伏期)与IDRS高风险显著相关(比值比1.085,可信区间[1.008, 1.168],P =.01),平均睡眠潜伏期/入睡时间(最大范围5[>1.5小时],众数2[10至30分钟])分钟。中度压力与睡眠质量差显著相关(比值比1.659)。

结论

睡眠质量差和压力与糖尿病呈正相关,且IDRS高风险人群的睡眠潜伏期增加,这表明可改变的风险因素发挥了作用。通过瑜伽进行行为改变和减轻压力可能有助于更好地管理糖尿病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5645/8455005/242b355a74a6/10.1177_0972753121998470-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5645/8455005/242b355a74a6/10.1177_0972753121998470-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5645/8455005/242b355a74a6/10.1177_0972753121998470-fig1.jpg

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