Rupprecht Charles E, Abela-Ridder Bernadette, Abila Ronello, Amparo Anna Charinna, Banyard Ashley, Blanton Jesse, Chanachai Karoon, Dallmeier Kai, de Balogh Katinka, Del Rio Vilas Victor, Ertl Hildegund, Freuling Conrad, Hill Richard, Houillon Guy, Jakava-Viljanen Miia, Kasemsuwan Suwicha, Léchenet Jacques, Nel Louis, Panichabhongse Pranee, Rahman Sira Abdul, Tantawichien Terapong, Vandeputte Joris, Viriyabancha Wittawat, Vos Ad, Wallace Ryan, Yale Gowri, Yurachai Onphirul, Mueller Thomas
LYSSA LLC, Atlanta, GA, USA.
World Health Organization (WHO), Geneva, Switzerland.
Biologicals. 2020 Mar;64:83-95. doi: 10.1016/j.biologicals.2020.01.008. Epub 2020 Feb 20.
Rabies is a major neglected zoonotic disease and causes a substantial burden in the Asian region. Currently, Pacific Oceania is free of rabies but enzootic areas throughout southeast Asia represent a major risk of disease introduction to this region. On September 25-26, 2019, researchers, government officials and related stakeholders met at an IABS conference in Bangkok, Thailand to engage on the topic of human rabies mediated by dogs. The objective of the meeting was focused upon snowballing efforts towards achieving substantial progress in rabies prevention, control and elimination within Asia by 2030, and thereby to safeguard the Pacific region. Individual sessions focused upon domestic animal, wildlife and human vaccination; the production and evaluation of quality, safety and efficacy of existing rabies biologics; and the future development of new products. Participants reviewed the progress to date in eliminating canine rabies by mass vaccination, described supportive methods to parenteral administration by oral vaccine application, considered updated global and local approaches at human prophylaxis and discussed the considerable challenges ahead. Such opportunities provide continuous engagement on disease management among professionals at a trans-disciplinary level and promote new applied research collaborations in a modern One Health context.
狂犬病是一种主要的被忽视的人畜共患疾病，在亚洲地区造成了巨大负担。目前，太平洋大洋洲没有狂犬病，但东南亚的动物疫病流行区是该病传入该地区的主要风险。2019年9月25日至26日，研究人员、政府官员及相关利益攸关方在泰国曼谷举行的一次国际狂犬病学会会议上，就犬介导的人类狂犬病这一主题进行了探讨。会议的目标集中在加大努力，以便到2030年在亚洲狂犬病的预防、控制和消除方面取得实质性进展，从而保护太平洋地区。各个分会场聚焦于家畜、野生动物及人类疫苗接种；现有狂犬病生物制品的质量、安全性和有效性的生产与评估；以及新产品的未来开发。与会者回顾了通过大规模疫苗接种消除犬狂犬病迄今取得的进展，描述了通过口服疫苗应用支持非肠道给药的方法，考虑了人类预防方面最新的全球和地方方法，并讨论了未来面临的重大挑战。此类机会促使跨学科层面的专业人员持续参与疾病管理，并在现代“同一健康”背景下推动新的应用研究合作。
