Assessment of Pathogenic Potential, Virulent Genes Profile, and Antibiotic Susceptibility of from Urinary Tract Infection.

is the third most common bacterium that can cause complicated UTI, especially in catheterized patients. Urovirulence genes of strains are poorly identified among UTI patients. The aims of the present study were to determine the prevalence of the uropathogenic strains isolated from UTI patients by the detection of several virulence genes and to characterize the antibiotic susceptibility profile of isolates. isolates were collected from urine specimens of patients suffering from UTI. Virulence genes in , namely, , , , , , , , , , , and were detected in the isolates via PCR detection method. All virulence genes were detected in more than 90% of the isolates except gene, which was detected in only 23.8% of the isolates. The rate of susceptibility for ceftriaxone was 96.8%, followed by norfloxacin (82.5%), gentamicin (71.4%), ciprofloxacin (69.8%), cephalexin (52.4%), nalidixic acid (42.9%), sulfamethoxazole (39.7%), ampicillin (36.5%), and nitrofurantoin (3.2%). Significant associations ( < 0.05) were detected between antimicrobial susceptibility of each of the following antibiotics and the presence virulence genes. Cephalexin antimicrobial susceptibility was significantly associated with the presence each of ureC1 and atfC. Sulfamethoxazole antimicrobial susceptibility was significantly associated with the presence atfA. Ceftriaxone antimicrobial susceptibility was significantly associated with the presence each of , , , , , and . Nitrofurantoin antimicrobial susceptibility was significantly associated with the presence each of , , , , , , and . In conclusion, an association between the presence of urovirulence genes of and increasing resistance to antimicrobials has been demonstrated.