人类非编码 RNA 基因命名指南。
A guide to naming human non-coding RNA genes.
机构信息
Department of Haematology, University of Cambridge School of Clinical Medicine, Cambridge, UK.
European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
出版信息
EMBO J. 2020 Mar 16;39(6):e103777. doi: 10.15252/embj.2019103777. Epub 2020 Feb 24.
Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, www.genenames.org) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.
非编码 RNA（ncRNA）的研究是一个快速发展的领域。为 ncRNA 基因提供官方的基因符号和名称，为其带来秩序，避免了潜在的混乱，使人们能够明确地交流每个基因。人类基因命名委员会（HGNC，www.genenames.org）是唯一有权批准人类基因符号的组织。HGNC 与不同类型 ncRNA 的专家顾问合作，以确保 ncRNA 命名法准确且信息丰富（在可能的情况下）。在这里，我们回顾了目前在人类基因组中注释的每一类主要 ncRNA，并描述了如何为每一类分配标准化的命名法。
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