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萜类化合物在 L.中的抗炎潜力

Anti-inflammatory Potential of Terpenes Present in L.

机构信息

Discipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland.

出版信息

ACS Chem Neurosci. 2020 Mar 4;11(5):659-662. doi: 10.1021/acschemneuro.0c00075. Epub 2020 Feb 24.

Abstract

L. () contains an array of plant-derived (phyto) cannabinoids and terpenes that are predominantly located in the trichome cavity of the plant. Terpenes, aromatic organic hydrocarbons characterized for their role in plant protection/pollination, are gaining attention for their potential as novel therapeutics in many areas of biomedicine. This Viewpoint will explore the exciting recent evidence that terpenes have anti-inflammatory/antioxidant propensity by targeting inflammatory signaling mechanisms relevant to human disease. Given their anti-inflammatory properties, terpenes may contribute to the effects of current cannabinoid-based therapies.

摘要

大麻二酚(CBD)中含有一系列植物源(植物)大麻素和萜烯,主要位于植物的毛状体腔中。萜烯是具有保护/授粉作用的芳香有机碳氢化合物,因其在生物医学许多领域作为新型治疗剂的潜力而受到关注。本观点将探讨最近令人兴奋的证据,即萜烯通过靶向与人类疾病相关的炎症信号机制具有抗炎/抗氧化特性。鉴于其抗炎特性,萜烯可能有助于目前基于大麻素的治疗方法的效果。

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