Discipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland.
ACS Chem Neurosci. 2020 Mar 4;11(5):659-662. doi: 10.1021/acschemneuro.0c00075. Epub 2020 Feb 24.
L. () contains an array of plant-derived (phyto) cannabinoids and terpenes that are predominantly located in the trichome cavity of the plant. Terpenes, aromatic organic hydrocarbons characterized for their role in plant protection/pollination, are gaining attention for their potential as novel therapeutics in many areas of biomedicine. This Viewpoint will explore the exciting recent evidence that terpenes have anti-inflammatory/antioxidant propensity by targeting inflammatory signaling mechanisms relevant to human disease. Given their anti-inflammatory properties, terpenes may contribute to the effects of current cannabinoid-based therapies.
大麻二酚(CBD)中含有一系列植物源(植物)大麻素和萜烯,主要位于植物的毛状体腔中。萜烯是具有保护/授粉作用的芳香有机碳氢化合物,因其在生物医学许多领域作为新型治疗剂的潜力而受到关注。本观点将探讨最近令人兴奋的证据,即萜烯通过靶向与人类疾病相关的炎症信号机制具有抗炎/抗氧化特性。鉴于其抗炎特性,萜烯可能有助于目前基于大麻素的治疗方法的效果。