Lanier A P, Bulkow L R, Ireland B
Arctic Investigations Laboratory, Center for Infectious Disease, Anchorage, AK 99501.
Public Health Rep. 1989 Nov-Dec;104(6):658-64.
The authors collected and analyzed cancer incidence data for Alaska Natives (Indians, Eskimos, and Aleuts) for the 15-year period 1969-83 by ethnic and linguistic groups. Compared with U.S. whites, observed-to-expected ratios are high in more than one ethnic group for cancer of the nasopharynx, salivary gland, liver, gallbladder, and cervix. Low ratios were found for cancer of the breast, uterus, bladder, and melanoma. In Alaska, Eskimos have the highest risk for cancer of the esophagus and liver and the lowest risk for breast and prostate cancer. Risk for multiple myeloma in Indian men in Alaska exceeds not only those of other Native groups in Alaska but that in U.S. whites as well. Despite the short period studied, increases in cancer incidence over time can be documented for lung cancer in Eskimo men and women combined, and for cervical cancer, especially in Indian women.
作者按种族和语言群体收集并分析了1969年至1983年这15年间阿拉斯加原住民（印第安人、爱斯基摩人和阿留申人）的癌症发病率数据。与美国白人相比，在不止一个种族群体中，鼻咽癌、唾液腺癌、肝癌、胆囊癌和宫颈癌的观察到预期发病率之比很高。乳腺癌、子宫癌、膀胱癌和黑色素瘤的发病率之比则较低。在阿拉斯加，爱斯基摩人患食管癌和肝癌的风险最高，患乳腺癌和前列腺癌的风险最低。阿拉斯加印第安男性患多发性骨髓瘤的风险不仅超过阿拉斯加其他原住民群体，也超过美国白人。尽管研究时间较短，但仍可记录到爱斯基摩男性和女性肺癌以及宫颈癌（尤其是印第安女性宫颈癌）的发病率随时间增加。
