Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts, USA.
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Eur Psychiatry. 2020 Feb 24;63(1):e21. doi: 10.1192/j.eurpsy.2019.11.
A growing body of research suggests that deficient emotional self-regulation (DESR) is common and morbid among attention-deficit/hyperactivity disorder (ADHD) patients. The main aim of the present study was to assess whether high and low levels of DESR in adult ADHD patients can be operationalized and whether they are clinically useful.
A total of 441 newly referred 18- to 55-year-old adults of both sexes with Diagnostic and Statistical Manual of Mental Disorders: Fifth Edition (DSM-5) ADHD completed self-reported rating scales. We operationalized DESR using items from the Barkley Current Behavior Scale. We used receiver operator characteristic (ROC) curves to identify the optimal cut-off on the Barkley Emotional Dysregulation (ED) Scale to categorize patients as having high- versus low-level DESR and compared demographic and clinical characteristics between the groups.
We averaged the optimal Barkley ED Scale cut-points from the ROC curve analyses across all subscales and categorized ADHD patients as having high- (N = 191) or low-level (N = 250) DESR (total Barkley ED Scale score ≥8 or <8, respectively). Those with high-level DESR had significantly more severe symptoms of ADHD, executive dysfunction, autistic traits, levels of psychopathology, and worse quality of life compared with those with low-level DESR. There were no major differences in outcomes among medicated and unmedicated patients.
High levels of DESR are common in adults with ADHD and when present represent a burdensome source of added morbidity and disability worthy of further clinical and scientific attention.
越来越多的研究表明,注意力缺陷多动障碍(ADHD)患者普遍存在且病态的情绪自我调节不足(DESR)。本研究的主要目的是评估成年 ADHD 患者中高和低水平的 DESR 是否可以操作化,以及它们是否具有临床意义。
共有 441 名新转诊的 18 至 55 岁的男女两性成年 ADHD 患者完成了自我报告的评定量表。我们使用 Barkley 当前行为量表的项目来操作 DESR。我们使用接收者操作特征(ROC)曲线来确定 Barkley 情绪失调(ED)量表上的最佳截断值,以将患者归类为高或低水平的 DESR,并比较两组之间的人口统计学和临床特征。
我们平均了 ROC 曲线分析中所有子量表的最佳 Barkley ED 量表截断点,并将 ADHD 患者归类为高(N = 191)或低水平(N = 250)DESR(总 Barkley ED 量表评分≥8 或 <8,分别)。与低水平 DESR 相比,高水平 DESR 的 ADHD、执行功能、自闭症特征、精神病理学水平和生活质量更差的症状明显更严重。在接受和未接受药物治疗的患者中,结果没有明显差异。
高水平的 DESR 在成年 ADHD 患者中很常见,并且当存在时,代表了一种额外的病态和残疾的负担源,值得进一步的临床和科学关注。