Clinical and Research Programs in Pediatric Psychopharmacologyand Adult ADHD, Massachusetts General Hospital, Boston, MA 02114-3139, USA.
Pediatrics. 2013 Sep;132(3):e612-22. doi: 10.1542/peds.2012-3947. Epub 2013 Aug 26.
To assess the implications of autistic traits (ATs) in youth with attention-deficit/hyperactivity disorder (ADHD) without a diagnosis of autism.
Participants were youth with (n = 242) and without (n = 227) ADHD and controls without ADHD in whom a diagnosis of autism was exclusionary. Assessment included measures of psychiatric, psychosocial, educational, and cognitive functioning. ATs were operationalized by using the withdrawn + social + thought problems T scores from the Child Behavior Checklist.
A positive AT profile was significantly overrepresented among ADHD children versus controls (18% vs 0.87%; P < .001). ADHD children with the AT profile were significantly more impaired than control subjects in psychopathology, interpersonal, school, family, and cognitive domains.
A substantial minority of ADHD children manifests ATs, and those exhibiting ATs have greater severity of illness and dysfunction.
评估自闭症特质(ATs)在未被诊断为自闭症的注意力缺陷/多动障碍(ADHD)青少年中的影响。
参与者包括有(n=242)和无(n=227)ADHD 的青少年以及排除 ADHD 诊断的对照组。评估包括精神、心理社会、教育和认知功能的测量。自闭症特质通过儿童行为检查表的退缩+社交+思维问题 T 分数来操作化。
与对照组相比,ADHD 儿童的阳性 AT 特征显著更多(18%比 0.87%;P<.001)。具有 AT 特征的 ADHD 儿童在精神病理学、人际关系、学校、家庭和认知领域的受损程度明显高于对照组。
相当一部分 ADHD 儿童表现出 ATs,而表现出 ATs 的儿童病情和功能障碍更为严重。