Norwegian Institute of Public Health, Norway; and
Norwegian Institute of Public Health, Norway; and.
Pediatrics. 2020 Mar;145(3). doi: 10.1542/peds.2019-2007. Epub 2020 Feb 24.
Maternal drinking is associated with child emotional and behavior problems. There is, however, a lack of studies that properly account for confounding. Our objective was to estimate the association between at-risk drinking in mothers of young children and child emotional and behavior problems, taking into account the passive transmission of familial risk.
This population-based sample consists of 34 039 children nested within 21 911 nuclear families and 18 158 extended families from the Norwegian Mother, Father, and Child Cohort Study. Participants were recruited between 1999 and 2009 during routine ultrasound examinations. Data were collected during the 17th and 30th gestational week and when the children were 1.5, 3, and 5 years old. We applied a multilevel structural equation model that accounted for unobserved familial risks.
Children of mothers with at-risk drinking had a higher likelihood of behavior problems (β = 3.53; 95% confidence interval [CI] 3.01 to 4.05) than children of mothers with low alcohol consumption. This association was reduced after adjusting for factors in the extended family (β = 1.93; 95% CI 1.16 to 2.71) and the nuclear family (β = 1.20; 95% CI 0.39 to 2.01). Maternal at-risk drinking had a smaller association with child emotional problems (β = 1.80; 95% CI 1.26 to 2.34). This association was reduced after adjusting for factors in the extended family (β = 0.67; 95% CI -0.12 to 1.46) and the nuclear family (β = 0.58; 95% CI -0.31 to 1.48).
The results suggest an association between maternal at-risk drinking and child behavior problems. A reduction in maternal drinking may improve outcomes for children with such symptoms.
母亲饮酒与儿童情绪和行为问题有关。然而，目前缺乏充分考虑混杂因素的研究。本研究旨在评估幼儿期母亲的危险饮酒行为与儿童情绪和行为问题之间的关联，并考虑家族风险的被动传递。
本研究采用基于人群的样本，来自挪威母婴儿童队列研究中的 34039 名儿童，嵌套在 21911 个核心家庭和 18158 个扩展家庭中。参与者于 1999 年至 2009 年期间在常规超声检查时招募。数据收集于妊娠第 17 周和第 30 周以及儿童 1.5、3 和 5 岁时进行。本研究采用多水平结构方程模型，考虑了未观察到的家族风险。
与低酒精摄入母亲的孩子相比，母亲有危险饮酒行为的孩子更有可能出现行为问题（β=3.53；95%置信区间 [CI] 3.01 至 4.05）。在调整扩展家庭（β=1.93；95% CI 1.16 至 2.71）和核心家庭（β=1.20；95% CI 0.39 至 2.01）因素后，这种关联有所减弱。母亲的危险饮酒行为与儿童情绪问题的关联较小（β=1.80；95% CI 1.26 至 2.34）。在调整扩展家庭（β=0.67；95% CI -0.12 至 1.46）和核心家庭（β=0.58；95% CI -0.31 至 1.48）因素后，这种关联也有所减弱。
结果表明，母亲的危险饮酒行为与儿童的行为问题有关。减少母亲的饮酒量可能会改善有此类症状的儿童的结局。
