Suppr超能文献

腰椎椎管狭窄症在一般人群和临床人群中的患病率:系统评价和荟萃分析。

Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis.

机构信息

Department of Sports Science and Clinical Biomechanics, Center for Muscle and Joint Health, University of Southern Denmark, Odense, Denmark.

Nordic Institute of Chiropractic and Clinical Biomechanics, Odense, Denmark.

出版信息

Eur Spine J. 2020 Sep;29(9):2143-2163. doi: 10.1007/s00586-020-06339-1. Epub 2020 Feb 24.

Abstract

PURPOSE

To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria.

METHODS

Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calculated and plotted [PROSPERO ID: CRD42018109640].

RESULTS

In total, 41 papers reporting on 55 study samples were included. The overall risk of bias was considered high in two-thirds of the papers. The mean prevalence, based on a clinical diagnosis of LSS in the general population, was 11% (95% CI 4-18%), 25% (95% CI 19-32%) in patients from primary care, 29% (95% CI 22-36%) in patients from secondary care and 39% (95% CI 39-39%) in patients from mixed primary and secondary care. Evaluating the presence of LSS based on radiological diagnosis, the pooled prevalence was 11% (95% CI 5-18%) in the asymptomatic population, 38% (95% CI - 10 to 85%) in the general population, 15% (95% CI 13-18%) in patients from primary care, 32% (95% CI 22-41%) in patients from secondary care and 21% (95% CI 16-26%) in a mixed population from primary and secondary care.

CONCLUSIONS

The mean prevalence estimates based on clinical diagnoses vary between 11 and 39%, and the estimates based on radiological diagnoses similarly vary between 11 and 38%. The results are based on studies with high risk of bias, and the pooled prevalence estimates should therefore be interpreted with caution. With an growing elderly population, there is a need for future low risk-of-bias research clarifying clinical and radiological diagnostic criteria of lumbar spinal stenosis. These slides can be retrieved under Electronic Supplementary Material.

摘要

目的

评估成人临床症状和/或影像学标准诊断的退行性腰椎椎管狭窄症(LSS)的患病率。

方法

系统文献复习。按医疗环境和临床或影像学诊断标准计算并绘制了汇总患病率估计值[PROSPERO ID:CRD42018109640]。

结果

共纳入 41 篇报告 55 项研究样本的论文。三分之二的论文被认为存在高偏倚风险。基于普通人群中 LSS 的临床诊断,总体患病率为 11%(95%CI 4-18%),初级保健患者为 25%(95%CI 19-32%),二级保健患者为 29%(95%CI 22-36%),混合初级和二级保健患者为 39%(95%CI 39-39%)。基于影像学诊断评估 LSS 的存在,无症状人群的汇总患病率为 11%(95%CI 5-18%),普通人群为 38%(95%CI-10 至 85%),初级保健患者为 15%(95%CI 13-18%),二级保健患者为 32%(95%CI 22-41%),初级和二级保健混合人群为 21%(95%CI 16-26%)。

结论

基于临床诊断的患病率估计值平均在 11%至 39%之间,基于影像学诊断的患病率估计值同样在 11%至 38%之间波动。这些结果基于存在高偏倚风险的研究,因此汇总患病率估计值应谨慎解读。随着老年人口的增长,需要未来进行低偏倚风险研究,以明确腰椎椎管狭窄的临床和影像学诊断标准。这些幻灯片可在电子补充材料中检索。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验