Li Xin, Ding Xinyue, Cui Wei, Song Xinwang, Shi Chunyan, Li Xiangdong
Institute of Biomedical Engineering, Yanshan University, Qinhuangdao, Hebei 066004, P.R.China;Measurement Technology and Instrumentation Key Lab of Hebei Province, Qinhuangdao, Hebei 066004, P.R.China.
HanDan Central Hospital, Handan, Hebei 056000, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Feb 25;37(1):54-60. doi: 10.7507/1001-5515.201904012.
Sub-threshold depression refers to a psychological sub-health state that fails to meet the diagnostic criteria for depression. Appropriate intervention can improve the state and reduce the risks of disease development. In this paper, we focus on music neurofeedback stimulation improving emotional state of sub-threshold depression college students.Twenty-four college students with sub-threshold depression participated in the experiment, 16 of whom were members of the experimental group. Decompression music based on spectrum classification was applied to 16 experimental group participants for 10 min/d music neural feedback stimulation with a period of 14 days, and no stimulation was applied to 8 control group participants. Three feature parameters of electroencephalogram (EEG) relative power, sample entropy and complexity were extracted for analysis. The results showed that the relative power of α、β and θ rhythm increased, while δ rhythm decreased after the stimulation of musical nerofeedback in the experimental group. The sample entropy and complexity were significantly increased after the stimulation, and the differences of these parameters pre and post stimulation were statistically significant ( < 0.05), while the differences of all feature parameters in the control group were not statistically significant. In the experimental group, the scores of self-rating depression scale(SDS) decreased after the stimulation of musical nerofeedback, indicating that the depression was improved. The result of this study showed that music neurofeedback stimulation can improve sub-threshold depression and may provides an effective new way for college students to self-regulation of emotion.
亚阈值抑郁是指未达到抑郁症诊断标准的一种心理亚健康状态。适当的干预可以改善这种状态并降低疾病发展的风险。在本文中，我们聚焦于音乐神经反馈刺激对亚阈值抑郁大学生情绪状态的改善作用。24名患有亚阈值抑郁的大学生参与了实验，其中16名是实验组成员。对16名实验组参与者应用基于频谱分类的减压音乐，进行每天10分钟、为期14天的音乐神经反馈刺激，而8名对照组参与者不接受刺激。提取脑电图（EEG）的三个特征参数，即相对功率、样本熵和复杂度进行分析。结果显示，实验组在音乐神经反馈刺激后，α、β和θ节律的相对功率增加，而δ节律降低。刺激后样本熵和复杂度显著增加，刺激前后这些参数的差异具有统计学意义（<0.05），而对照组所有特征参数的差异无统计学意义。在实验组中，音乐神经反馈刺激后自评抑郁量表（SDS）得分降低，表明抑郁状况得到改善。本研究结果表明，音乐神经反馈刺激可以改善亚阈值抑郁，并可能为大学生情绪自我调节提供一种有效的新途径。
