Department of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Analyst. 2020 Apr 21;145(8):2854-2872. doi: 10.1039/c9an01987a. Epub 2020 Feb 25.
Due to the increase in the number of cancer patients, because of environmental parameters, high stress, low immunity, etc., there is an urgent need to develop cost-effective sensors for early targeted detection of cancerous cells with adequate selectivity and efficiency. Early disease diagnosis is important, as it is necessary to start treatments before disease progression. On the other hand, we need new, more efficient cancer treatment approaches with minimized side effects, more biocompatibility, and easy disposal. Nanobiotechnology is a field that can assist in developing new diagnostic and treatment approaches, specifically in fatal cancers. Herein, a study on the different applications of nanofibers in cancer detection as well as its treatment has been done. Here, a very brief survey on the main structure of biosensors and their different categories has been conducted and will precede the discussion of the study to serve as a reference and guide the reader's understanding.
由于癌症患者数量的增加，以及环境参数、高压力、低免疫力等因素，我们迫切需要开发具有足够选择性和效率的经济实惠的传感器，用于早期靶向检测癌细胞。早期疾病诊断非常重要，因为需要在疾病进展之前开始治疗。另一方面，我们需要新的、更有效的癌症治疗方法，副作用最小化、更好的生物相容性和易于处理。纳米生物技术是一个可以帮助开发新的诊断和治疗方法的领域，特别是在致命癌症方面。本文研究了纳米纤维在癌症检测和治疗中的不同应用。在此，对生物传感器的主要结构及其不同类别进行了简要调查，将在讨论研究之前进行，作为参考并指导读者的理解。
