Faculty of Food Science and Technology, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.
Department of Animal Science and Food Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Adv Colloid Interface Sci. 2020 Apr;278:102122. doi: 10.1016/j.cis.2020.102122. Epub 2020 Feb 11.
Encapsulation technology, as a promising approach, has been employed for the protection and controlled release of different bioactive compounds including natural antioxidants; there are restrictions for applying these valuable ingredients in real food products, pharmaceuticals, and cosmetics such as low solubility, low shelf life, difficultly in their packaging and handling, losses due to environmental stresses and food processes, undesirable flavors and odors, untargeted release and instability in various conditions during digestion in gastrointestinal tract. Nanocarriers can be employed to overcome these challenges. There are five groups of nanocarriers based on the principal mechanism/ingredient used to make them for the encapsulation of natural antioxidants titled biopolymeric nanoparticles, lipid-based and surfactant-based nanocarriers, nanocarriers made with specially designed equipment, nature-inspired nanocarriers, and miscellaneous ones. The main goal of this study is to have an overview of role of different nanocarriers in improving the efficiency of natural antioxidant compounds for different purposes. It has been verified that antioxidant-loaded nanocarriers can be applied in many formulations with a higher and controlled release antioxidant activity, which would meet the current needs of consumers' expectations towards clean label products.
包封技术作为一种有前途的方法,已被用于保护和控制不同生物活性化合物的释放,包括天然抗氧化剂;然而,将这些有价值的成分应用于实际食品产品、制药和化妆品中存在一些限制,如低溶解度、低保质期、包装和处理困难、环境压力和食品加工过程中的损失、不良味道和气味、靶向释放困难以及在胃肠道消化过程中的各种条件下的不稳定性。纳米载体可用于克服这些挑战。基于用于制造它们的主要机制/成分,有五类纳米载体可用于封装天然抗氧化剂,分别是:生物聚合物纳米颗粒、基于脂质和表面活性剂的纳米载体、用专门设计的设备制造的纳米载体、受自然启发的纳米载体和其他类型的纳米载体。本研究的主要目的是概述不同纳米载体在提高天然抗氧化剂化合物用于不同目的的效率方面的作用。已经证实,负载抗氧化剂的纳米载体可以应用于许多制剂中,具有更高和可控的抗氧化剂释放活性,这将满足消费者对清洁标签产品的期望的当前需求。