Yang Shanshan, Liu Miao, Wang Shengshu, Jia Wangping, Han Ke, He Yao
Institute of Geriatrics, State Key Laboratory of Kidney Disease, Beijing Key Laboratory of Aging and Geriatrics, The 2nd Clinical Center, Chinese PLA General Hospital, Beijing 100853, People's Republic of China.
Department of Disease Control, Northern Military Area Center for Disease Control and Prevention, Jinan, People's Republic of China.
Diabetes Metab Syndr Obes. 2020 Feb 4;13:277-287. doi: 10.2147/DMSO.S231435. eCollection 2020.
To analyze the associations between waist circumference (WC), body mass index (BMI), waist-hip ratio (WHR), waist-height ratio (WHtR), calf circumference, waist-calf circumference ratio (WCR), and quality of life in Hainan centenarians.
A total of 1002 centenarians in Hainan were selected by a full sample survey. The EQ-5D visual analogue scale (EQ-5D-VAS) was used to investigate the quality of life. Restricted cubic splines were used to analyze and visualize the linear relationships.
After adjustment, the standard β values for BMI, WC, WHR, WHtR, calf circumference, and WCR associated with EQ-5D score were 0.101, 0.126, -0.018, 0.100, 0.302, and -0.219, respectively; all associations except for WHR were significant (P < 0.01). With increasing BMI, WC, and calf circumference, the risk of EQ-5D score <1 decreased (odds ratios [ORs] 0.91 [95% confidence interval (CI): 0.86-0.97), 0.97 [95% CI: 0.95-0.99], and 0.87 [95% CI: 0.82-0.92] after adjustment, respectively). With increasing WCR, the risk also increased (OR 2.70 [95% CI: 1.54-4.75]).
After excluding nutritional and muscle retention factors, fat central distribution negatively impacted the health-related quality of life of the oldest old population.
分析海南百岁老人的腰围（WC）、体重指数（BMI）、腰臀比（WHR）、腰高比（WHtR）、小腿围、腰围与小腿围之比（WCR）与生活质量之间的关联。
通过全样本调查选取了1002名海南百岁老人。采用欧洲五维度健康量表视觉模拟评分法（EQ-5D-VAS）调查生活质量。使用受限立方样条来分析和可视化线性关系。
调整后，与EQ-5D评分相关的BMI、WC、WHR、WHtR、小腿围和WCR的标准化β值分别为0.101、0.126、-0.018、0.100、0.302和-0.219；除WHR外，所有关联均具有统计学意义（P<0.01）。随着BMI、WC和小腿围的增加，EQ-5D评分<1的风险降低（调整后的比值比[OR]分别为0.91[95%置信区间（CI）：0.86-0.97]、0.97[95%CI：0.95-0.99]和0.87[95%CI：0.82-0.92]）。随着WCR的增加，风险也增加（OR 2.70[95%CI：1.54-4.75]）。
排除营养和肌肉保留因素后，脂肪中心分布对高龄老人的健康相关生活质量产生负面影响。
