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过渡期山羊骨代谢生物标志物的血清浓度

Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period.

作者信息

Tharwat Mohamed

机构信息

Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, P.O. Box 6622, Buraidah 51452, Saudi Arabia.

Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.

出版信息

Vet Med Int. 2020 Jan 31;2020:4064209. doi: 10.1155/2020/4064209. eCollection 2020.

DOI:10.1155/2020/4064209
PMID:32099639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7013289/
Abstract

OBJECTIVE

During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP), and pyridinoline cross-links (PYD).

METHOD

Blood samples were collected from fifteen female goats during the periparturient period 3 wk before expected parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition (.

RESULTS

Compared to a value of 77.67 ± 47.6 ng/mL at -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at.

CONCLUSION

The results of this study showed that the bone formation biomarkers (OC and b-ALP) did not change significantly during the periparturient period, while the bone resorption biomarker decreased significantly at parturition compared to 3 wk before and 3 wk after parturition. The significantly increased serum estrogen around parturition may have had a role in the increased bone resorption at this time.

摘要

目的

在过渡期,动物会经历一系列营养、生理和社会变化。本研究的目的是评估山羊围产期对骨生物标志物骨钙素(OC)、骨特异性碱性磷酸酶(b-ALP)和吡啶啉交联物(PYD)血清浓度的影响。

方法

在围产期从15只母羊采集血样,预期分娩前3周(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(.

结果

与-3时77.67±47.6 ng/mL的值相比,分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(>0.05)。与-3时42.00±19.50 U/L的值相比,分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(-3)、分娩后12小时内(>0.05)。与-3时42.00±19.50 U/L的值相比,分娩后12小时内(-3)、分娩后12小时内(>0.05)。与-3时42.00±19.50 U/L的值相比,分娩后12小时内(-3)、分娩后12小时内(>0.05)。与-3时42.00±19.50 U/L的值相比,在.

结论

本研究结果表明,骨形成生物标志物(OC和b-ALP)在围产期没有显著变化,而骨吸收生物标志物在分娩时与分娩前3周和分娩后3周相比显著降低。分娩前后血清雌激素显著升高可能在此时骨吸收增加中起作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/ace1927704fa/VMI2020-4064209.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/4cf849444c4d/VMI2020-4064209.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/ac9e855f84d5/VMI2020-4064209.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/ace1927704fa/VMI2020-4064209.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/4cf849444c4d/VMI2020-4064209.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/ac9e855f84d5/VMI2020-4064209.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d70/7013289/ace1927704fa/VMI2020-4064209.003.jpg

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