Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period.

OBJECTIVE

During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP), and pyridinoline cross-links (PYD).

METHOD

Blood samples were collected from fifteen female goats during the periparturient period 3 wk before expected parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition (.

RESULTS

Compared to a value of 77.67 ± 47.6 ng/mL at -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at -3), within 12 h of parturition ( -3), within 12 h of parturition ( > 0.05). Compared to a value of 42.00 ± 19.50 U/L at.

CONCLUSION

The results of this study showed that the bone formation biomarkers (OC and b-ALP) did not change significantly during the periparturient period, while the bone resorption biomarker decreased significantly at parturition compared to 3 wk before and 3 wk after parturition. The significantly increased serum estrogen around parturition may have had a role in the increased bone resorption at this time.