Bouayyad Sarah, Ong Jen, Bouayyad Houda, Woodun Heerani
Department of Otolaryngology, Tameside General Hospital, Ashton-under-Lyne, UK.
ENT Department, Royal Albert Edward Infirmary, Wigan, UK.
J Surg Case Rep. 2020 Feb 19;2020(2):rjaa009. doi: 10.1093/jscr/rjaa009. eCollection 2020 Feb.
Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.
颗粒细胞瘤是一种罕见的良性肿瘤，可发生于身体各处的软组织。它通常无症状，因此常被误诊为其他疾病。这是一例50岁无症状男性患者，在常规食管胃镜检查时偶然发现声门上病变。全身麻醉下检查发现会厌喉面有一个白色、非溃疡性、外生性病变，未累及前联合和声带。采用开放性声门上喉切除术进行手术切除。组织病理学确诊为颗粒细胞瘤，S-100蛋白呈强阳性，CD68呈弱阳性。准确的组织学分析是在其他鉴别诊断中识别这种罕见肿瘤的关键。尽管为良性，但鉴于有复发风险，建议进行持续监测。
