铜催化末端炔烃与芳基亚磺酸钠的二磺化反应
Copper-Catalyzed Disulfonation of Terminal Alkynes with Sodium Arylsulfinates.
作者信息
Liu Zhenhua, Yang Lin, Zhang Kaining, Chen Wanjiao, Yu Tian, Wang Lianxiao, Gao Wen, Tang Bo
机构信息
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan, 250014, P. R. China.
出版信息
Org Lett. 2020 Mar 6;22(5):2081-2086. doi: 10.1021/acs.orglett.0c00575. Epub 2020 Feb 26.
A novel and direct disulfonylation reaction of commercially available terminal alkynes under copper(I)/bromodifluoroacetate cocatalyst has been realized. This protocol provides a facile and practical pathway to selectively access (E)-1,2-disulfonylethenes, in which features good functional group compatibility, easily available starting materials, and excellent stereoselectivity with good yields.
在铜（I）/溴二氟乙酸酯共催化剂作用下，实现了市售末端炔烃新颖且直接的二磺酰化反应。该方法提供了一条简便实用的途径，可选择性地合成（E）-1,2-二磺酰基乙烯，其具有良好的官能团兼容性、易于获得的起始原料以及优异的立体选择性和良好的产率。
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