TORSKAL nanosciences, 2 rue Maxime Rivière, 97490, Sainte-Clotilde, La Réunion, France; CNRS, UMR 7244, CSPBAT, Laboratoire de Chimie, Structures et Propriétés de Biomateriaux et d'Agents Thérapeutiques, Université Paris 13, Sorbonne Paris Cité, Bobigny, France.
TORSKAL nanosciences, 2 rue Maxime Rivière, 97490, Sainte-Clotilde, La Réunion, France; LCSNSA - Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments - UR, Faculté des Sciences et Technologies, Université de La Réunion, 15 avenue René Cassin, France.
Colloids Surf B Biointerfaces. 2020 May;189:110855. doi: 10.1016/j.colsurfb.2020.110855. Epub 2020 Feb 11.
Hubertia ambavilla, an endemic plant originating from Reunion Island in the Indian Ocean, is traditionally used as an anti-inflammatory and in healing, both for internal and external use. Polyphenolic compounds from aqueous phase extractions can reduce metal salts into nanoparticles and stabilize them in one step. Although gold nanoparticles are well described in the literature as anti-ageing ingredients, the nanoparticles presented herein are novel and are synthesized using a green process. We demonstrate their efficiency as dermoprotective, free radical scavenger and antioxidant cosmetic ingredients. Comparison with common nanoparticles obtained by the Turkevich method clearly emphasizes the necessity to carefully screen the products used for nanoparticle coatings, as they play a major role in the biological properties of the product. Hubertia ambavilla mediated gold nanoparticles are non-toxic to human dermal fibroblasts, possess free radical scavenging potential, and protect against damage to fibroblast and dermal cells caused by ultraviolet A radiation.
Hubertia ambavilla 是一种原产于印度洋留尼汪岛的特有植物，传统上被用作抗炎和治疗药物，可内服或外用。水相提取物中的多酚化合物可以将金属盐还原成纳米颗粒，并一步稳定它们。尽管金纳米粒子在文献中被很好地描述为抗衰老成分，但本文所介绍的纳米粒子是新颖的，并且是使用绿色工艺合成的。我们证明了它们作为皮肤保护剂、自由基清除剂和抗氧化化妆品成分的功效。与通过 Turkevich 方法获得的常见纳米粒子进行比较，清楚地强调了有必要仔细筛选用于纳米粒子涂层的产品，因为它们在产品的生物特性中起着重要作用。Hubertia ambavilla 介导的金纳米粒子对人真皮成纤维细胞无毒，具有清除自由基的潜力，并能防止紫外线 A 辐射对成纤维细胞和真皮细胞造成的损伤。
