Fukushima Yoichi, Takahashi Yoshinari, Kishimoto Yoshimi, Taguchi Chie, Suzuki Norie, Yokoyama Mihoko, Kondo Kazuo
Wellness Communications Section, Nestlé Japan Ltd., Tokyo, Japan.
Inary Corp., Tokyo, Japan.
Clin Cosmet Investig Dermatol. 2020 Feb 10;13:165-172. doi: 10.2147/CCID.S225043. eCollection 2020.
Hyperpigmentation of the skin can occur at any age depending on etiological factors but its intensity increases during adolescence in Japanese females and gradually develops further in adults. The purpose of this study was to characterize factors that influence skin hyperpigmentation, including age, skin type and dietary polyphenol sources.
A cross-sectional survey of healthy Japanese women aged from 30 to 60 years (n=244) was conducted using food and environmental questionnaires and a VISIA™ facial photoimage analyzer.
UV Pigmented Spot (PS) scores correlated negatively with the consumption of total polyphenols (TPs) (R=-0.224, p<0.001) and the rate of hyperpigmented spot development (PS score/age after 18 years of age) was suppressed by the consumption of TPs. This trend was independent of the melanin index and the skin type, which indicates the ability of the skin to tan after sun exposure. Consumption of coffee, the largest source of TPs, suppressed the PS score (p<0.001). Consumption of green tea, the second largest source of TPs, also suppressed the PS score, which was weaker than coffee but was statistically significant (p=0.029). The PS score was suppressed the most in subjects with both a high consumption of coffee and green tea.
Higher consumption of TPs may be beneficial to alleviate photoaging of the skin, and coffee as well as green tea contribute to suppress skin hyperpigmentation through adding large amounts of TPs in the diet.
皮肤色素沉着可因病因不同而在任何年龄出现，但其严重程度在日本女性青春期会增加，并在成年期进一步逐渐发展。本研究旨在确定影响皮肤色素沉着的因素，包括年龄、皮肤类型和膳食多酚来源。
对244名年龄在30至60岁的健康日本女性进行横断面调查，使用食物和环境问卷以及VISIA™面部照片图像分析仪。
紫外线色素沉着斑（PS）评分与总多酚（TPs）的摄入量呈负相关（R = -0.224，p < 0.001），TPs的摄入抑制了色素沉着斑的发展速度（PS评分/18岁后的年龄）。这种趋势与黑色素指数和皮肤类型无关，皮肤类型指的是皮肤在阳光照射后晒黑的能力。TPs的最大来源咖啡的摄入抑制了PS评分（p < 0.001）。TPs的第二大来源绿茶的摄入也抑制了PS评分，其抑制作用虽弱于咖啡，但具有统计学意义（p = 0.029）。咖啡和绿茶摄入量都高的受试者的PS评分抑制最为明显。
较高的TPs摄入量可能有利于减轻皮肤光老化，咖啡和绿茶通过在饮食中添加大量TPs有助于抑制皮肤色素沉着。
