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Mechanical thrombectomy in stroke - planning for service expansion using discrete event simulation.中风的机械取栓术——使用离散事件模拟进行服务扩展规划
Future Healthc J. 2020 Feb;7(1):65-71. doi: 10.7861/fhj.2019-0003.
2
National implementation of reperfusion for acute ischaemic stroke in England: How should services be configured? A modelling study.英国急性缺血性卒中再灌注治疗的全国性实施:服务应如何配置?一项建模研究。
Eur Stroke J. 2022 Mar;7(1):28-40. doi: 10.1177/23969873211063323. Epub 2021 Dec 23.
3
4
Drip and ship and mothership models of mechanical thrombectomy result in similar outcomes in acute ischemic stroke of the anterior circulation.机械取栓的滴注-输送和母舰模型在前循环急性缺血性卒中的结果相似。
J Stroke Cerebrovasc Dis. 2022 Oct;31(10):106733. doi: 10.1016/j.jstrokecerebrovasdis.2022.106733. Epub 2022 Aug 26.
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Two Paradigms for Endovascular Thrombectomy After Intravenous Thrombolysis for Acute Ischemic Stroke.急性缺血性卒中静脉溶栓后血管内血栓切除术的两种模式
JAMA Neurol. 2017 May 1;74(5):549-556. doi: 10.1001/jamaneurol.2016.5823.
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Direct admission vs. secondary transfer for mechanical thrombectomy: long-term clinical outcomes from a single Polish Comprehensive Stroke Centre.直接入院与二次转院行机械取栓:来自波兰综合卒中中心的长期临床结局。
Neurol Neurochir Pol. 2021;55(5):494-498. doi: 10.5603/PJNNS.a2021.0050. Epub 2021 Aug 4.
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European Stroke Organisation (ESO)-European Society for Minimally Invasive Neurological Therapy (ESMINT) expedited recommendation on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion.欧洲卒中组织(ESO)-欧洲微创神经治疗学会(ESMINT)关于急性缺血性脑卒中前循环大血管闭塞患者机械取栓前静脉溶栓适应证的快速推荐意见。
J Neurointerv Surg. 2022 Mar;14(3):209. doi: 10.1136/neurintsurg-2021-018589. Epub 2022 Feb 3.
8
Hub-and-spoke model for thrombectomy service in UK NHS practice.英国国民保健制度实践中的取栓服务的轮辐式模型。
Clin Med (Lond). 2021 Jan;21(1):e26-e31. doi: 10.7861/clinmed.2020-0579.
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Mothership versus Drip-and-Ship for stroke in a rural area: A French prospective observational study.农村地区卒中的母舰式与点滴式转运模式:一项法国前瞻性观察性研究。
Rev Neurol (Paris). 2025 Jan-Feb;181(1-2):67-78. doi: 10.1016/j.neurol.2024.06.007. Epub 2024 Jul 29.
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Progression of cerebral infarction before and after thrombectomy is modified by prehospital pathways.取栓术前和术后的脑梗死进展由院前途径改变。
J Neurointerv Surg. 2022 May;14(5):485-9. doi: 10.1136/neurintsurg-2020-017155. Epub 2021 May 13.

引用本文的文献

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A retrospective audit of out-of-hours mechanical thrombectomy of anterior circulation large vessel occlusion in a UK tertiary centre.英国一家三级中心对机械取栓治疗前循环大血管闭塞的非工作时间回顾性审计。
Clin Med (Lond). 2023 Sep;23(5):491-494. doi: 10.7861/clinmed.2022-0395. Epub 2023 Sep 29.
2
Discrete-Event Simulation Modeling in Healthcare: A Comprehensive Review.医疗保健中的离散事件仿真建模:全面综述。
Int J Environ Res Public Health. 2021 Nov 22;18(22):12262. doi: 10.3390/ijerph182212262.
3
Hub-and-spoke model for thrombectomy service in UK NHS practice.英国国民保健制度实践中的取栓服务的轮辐式模型。
Clin Med (Lond). 2021 Jan;21(1):e26-e31. doi: 10.7861/clinmed.2020-0579.
4
Acknowledging and learning from smaller hospitals.认可并向小型医院学习。
Future Healthc J. 2020 Feb;7(1):1. doi: 10.7861/fhj.ed-7-1-1.

本文引用的文献

1
Estimating the number of UK stroke patients eligible for endovascular thrombectomy.估算英国适合进行血管内血栓切除术的中风患者数量。
Eur Stroke J. 2017 Dec;2(4):319-326. doi: 10.1177/2396987317733343. Epub 2017 Oct 4.
2
Brain ischemia: CT and MRI techniques in acute ischemic stroke.脑缺血:急性缺血性脑卒中的 CT 和 MRI 技术。
Eur J Radiol. 2017 Nov;96:162-172. doi: 10.1016/j.ejrad.2017.08.014. Epub 2017 Aug 24.
3
Drip 'n Ship Versus Mothership for Endovascular Treatment: Modeling the Best Transportation Options for Optimal Outcomes.血管内治疗中“点滴转运”与“母舰转运”的比较:为实现最佳结果模拟最佳转运方案
Stroke. 2017 Mar;48(3):791-794. doi: 10.1161/STROKEAHA.116.015321. Epub 2017 Jan 18.
4
Standards for providing safe acute ischaemic stroke thrombectomy services (September 2015).提供安全的急性缺血性中风血栓切除术服务的标准(2015年9月)
Clin Radiol. 2017 Feb;72(2):175.e1-175.e9. doi: 10.1016/j.crad.2016.11.008. Epub 2016 Dec 11.
5
Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis.血管内血栓切除术的治疗时间与缺血性中风的预后:一项荟萃分析。
JAMA. 2016 Sep 27;316(12):1279-88. doi: 10.1001/jama.2016.13647.
6
Analysis of Workflow and Time to Treatment and the Effects on Outcome in Endovascular Treatment of Acute Ischemic Stroke: Results from the SWIFT PRIME Randomized Controlled Trial.急性缺血性脑卒中血管内治疗的工作流程和治疗时间分析及其对结局的影响:来自 SWIFT PRIME 随机对照试验的结果。
Radiology. 2016 Jun;279(3):888-97. doi: 10.1148/radiol.2016160204. Epub 2016 Apr 19.
7
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.血管内血栓切除术治疗大动脉闭塞性缺血性卒中的Meta 分析:来自五项随机试验的个体患者数据汇总分析
Lancet. 2016 Apr 23;387(10029):1723-31. doi: 10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18.
8
Evaluation of a telephone advice system for remote intravenous thrombolysis in ischemic stroke: data from a United kingdom network.评价电话咨询系统在缺血性脑卒中患者远程静脉溶栓中的应用:来自英国网络的数据。
Stroke. 2015 Mar;46(3):867-9. doi: 10.1161/STROKEAHA.114.008190. Epub 2015 Jan 20.
9
Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score.定量计算机断层扫描评分在预测溶栓治疗前超急性卒中预后中的有效性和可靠性。ASPECTS研究组。阿尔伯塔卒中项目早期CT评分。
Lancet. 2000 May 13;355(9216):1670-4. doi: 10.1016/s0140-6736(00)02237-6.
10
Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group.通过视频培训提高美国国立卫生研究院卒中量表的可靠性。美国国立神经疾病与中风研究所组织型纤溶酶原激活剂卒中研究组。
Stroke. 1994 Nov;25(11):2220-6. doi: 10.1161/01.str.25.11.2220.

中风的机械取栓术——使用离散事件模拟进行服务扩展规划

Mechanical thrombectomy in stroke - planning for service expansion using discrete event simulation.

作者信息

Dutta Dipankar, Parry Frances, Obaid Mudhar, Ramadurai Gopinath

机构信息

Gloucestershire Royal Hospital, Gloucester, UK.

出版信息

Future Healthc J. 2020 Feb;7(1):65-71. doi: 10.7861/fhj.2019-0003.

DOI:10.7861/fhj.2019-0003
PMID:32104769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7032577/
Abstract

Mechanical thrombectomy (MT) is a very effective, but highly time dependent, reperfusion technique in the management of acute ischaemic stroke caused by large artery occlusion. MT is provided by 24 neuroscience centres (NSCs) in the UK which receive patients directly ('mothership') and via transfer from district general hospitals (DGHs), the 'drip and ship' pathway. NSCs currently provide a within hours service but are working on service expansion to enable 24/7 availability. DGHs, too, will need to prepare for this service expansion to ensure good outcomes for their patients. We discuss options for service expansion in a DGH and regional stroke network in south-west England and use Sentinel Stroke National Audit Programme data and discrete event simulation to model and compare alternative workflow options to aid the planning process. We suggest that our modelled options could be considered by all NHS DGHs in their preparation for MT service expansion.

摘要

机械取栓术(MT)是治疗由大动脉闭塞引起的急性缺血性卒中时一种非常有效的再灌注技术,但时间依赖性很强。英国有24个神经科学中心(NSCs)提供MT,这些中心直接接收患者(“母舰”模式),并通过从地区综合医院(DGHs)转运接收患者,即“点滴转运”途径。NSCs目前提供数小时内的服务,但正在努力扩大服务范围以实现全天候可用。DGHs也需要为这项服务扩展做好准备,以确保其患者获得良好的治疗效果。我们讨论了英格兰西南部一个DGH和区域卒中网络中服务扩展的选项,并使用哨兵卒中国家审计计划数据和离散事件模拟来建模和比较替代工作流程选项,以辅助规划过程。我们建议,所有国民保健服务DGHs在为MT服务扩展做准备时都可以考虑我们建模的选项。