[牛奶蛋白过敏或乳糖不耐受：大学生横断面研究]

[Allergy to cow's milk protein, or lactose intolerance: a cross-sectional study in university students].

作者信息

Domínguez-García Victoria, Flores-Merino Miriam V, Morales-Romero Jaime, Bedolla-Pulido Angie, Mariscal-Castro Juan, Bedolla-Barajas Martín

机构信息

Universidad Autónoma del Estado de México, Centro de Investigación en Ciencias Médicas, Estado de México, México.

出版信息

Rev Alerg Mex. 2019 Oct-Dec;66(4):394-402. doi: 10.29262/ram.v66i4.640.

DOI:10.29262/ram.v66i4.640

PMID:32105423

Abstract

BACKGROUND

Factors like ethnic origin and geographical area affect the frequency of cow's milk protein allergy (CMPA) and lactose intolerance (LI). Epidemiological information about the non-pediatric population is still missing.

OBJECTIVE

To determine the prevalence of CMPA and LI in university students.

METHODS

A cross-sectional study of 1200 students of 18 to 25-year-old. A structured questionnaire was applied in order to identify the clinical manifestations triggered by the intake of cow's milk (CM), and these were categorized as linked to CMPA or linked to LI.

RESULTS

Thirty students met the criteria for CMPA (prevalence of 2.5 %; CI 95 % = 1.7-3.6 %) and 128 for LI (prevalence of 10.7 %, CI 95 % = : 9.0 % - 12.5 %). The frequency of personal history of food allergy and dust mite allergy was higher in students with CMPA than in students with LI. Oral pruritus, skin and respiratory discomforts were predominant in CMPA. Abdominal cramps and flatulence were predominant in LI.

CONCLUSIONS

IL is more frequent than CMPA; which frequency was one in every 10 students; and the frequency of CMPA was one in 400.

摘要

背景

种族起源和地理区域等因素会影响牛奶蛋白过敏（CMPA）和乳糖不耐受（LI）的发生率。关于非儿科人群的流行病学信息仍然缺失。

目的

确定大学生中CMPA和LI的患病率。

方法

对1200名18至25岁的学生进行横断面研究。应用结构化问卷以识别摄入牛奶（CM）引发的临床表现，并将这些表现归类为与CMPA相关或与LI相关。

结果

30名学生符合CMPA标准（患病率为2.5%；95%置信区间=1.7-3.6%），128名学生符合LI标准（患病率为10.7%，95%置信区间=9.0%-12.5%）。CMPA学生的食物过敏和尘螨过敏个人史频率高于LI学生。口腔瘙痒、皮肤和呼吸道不适在CMPA中占主导。腹部绞痛和肠胃胀气在LI中占主导。