Papaioannou Theodore G, Protogerou Athanase D, Stamatelopoulos Kimon S, Alexandraki Krystallenia I, Vrachatis Dimitrios, Argyris Antonios, Papaioannou Vasilios, Vavuranakis Manolis, Stefanadis Christodoulos, Tousoulis Dimitrios
First Department of Cardiology, Biomedical Engineering Unit, Hippokration Hospital.
Department of Pathophysiology, Cardiovascular Prevention and Research Unit.
Blood Press Monit. 2020 Jun;25(3):131-135. doi: 10.1097/MBP.0000000000000435.
To characterize different patterns of variability of three repeated within-visit blood pressure (BP) readings and to determine the prevalence of specific variation trends in systolic (SBP), diastolic (DBP) blood pressure and pulse pressure (PP).
Data from 53 737 subjects from the National Health and Nutrition Examination Survey were analyzed. In each subject, three consecutive BP measurements were performed with a minimum time-interval of at least 30 s. We propose three patterns of within-visit BP variability (separately for SBP, DBP and PP): (1) increasing trend (BP3 > BP2 > BP1); (2) decreasing trend (BP1 > BP2 > BP3) and (3) no trend (BP3 ≈ BP2 ≈ BP1). A threshold of minimum change (ΔP > 3 mmHg) between BP1-BP2 and BP2-BP3 was also applied as a prerequisite for the definition of these trends.
An increasing trend was observed among three consecutive measurements of SBP, DBP and PP in 7.4, 10.4 and 10.2%, respectively. When a minimum threshold of 3 mmHg was set the respective increasing trends were observed in 1.8, 2.9 and 4.4%, respectively. There was a higher prevalence of decreasing trend within three consecutive SBP, DBP and PP readings: 17, 13.1 and 16.2%, respectively, whereas using a threshold of ΔP >3 mmHg the respective prevalence was 6.3, 4.1 and 7.7%. A maximum absolute difference >10 mmHg within triplicate of SBP/DBP/PP readings was observed in 12.9, 13 and 29.4%, respectively. In the era of personalized medicine, these patterns are well worth further investigation concerning their pathophysiologic and clinical relevance.
描述三次重复的就诊期间血压（BP）读数的不同变异模式，并确定收缩压（SBP）、舒张压（DBP）和脉压（PP）中特定变异趋势的患病率。
分析了来自国家健康与营养检查调查的53737名受试者的数据。对每个受试者进行三次连续的血压测量，最小时间间隔至少为30秒。我们提出了三种就诊期间血压变异性模式（分别针对SBP、DBP和PP）：（1）上升趋势（BP3＞BP2＞BP1）；（2）下降趋势（BP1＞BP2＞BP3）和（3）无趋势（BP3≈BP2≈BP1）。BP1 - BP2和BP2 - BP3之间最小变化阈值（ΔP＞3 mmHg）也被用作这些趋势定义的前提条件。
在SBP、DBP和PP的三次连续测量中，分别有7.4%、10.4%和10.2%观察到上升趋势。当设定3 mmHg的最小阈值时，相应的上升趋势分别在1.8%、2.9%和4.4%中观察到。在SBP、DBP和PP的三次连续读数中，下降趋势的患病率更高：分别为17%、13.1%和16.2%，而使用ΔP＞3 mmHg的阈值时，相应的患病率分别为6.3%、4.1%和7.7%。在SBP/DBP/PP读数的三次测量中，最大绝对差值＞10 mmHg分别在12.9%、13%和29.4%中观察到。在个性化医疗时代，这些模式在其病理生理和临床相关性方面非常值得进一步研究。
