• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

89 例髋臼周围转移瘤改良 Harrington 手术:一种可靠的方法,可获得良好的功能结果,特别是对预期生存时间较长的癌症患者。

Modified Harrington's procedure for periacetabular metastases in 89 cases: a reliable method for cancer patients with good functional outcome, especially with long expected survival.

机构信息

Department of Orthopaedics and Traumatology, Tampere University Hospital, Tampere.

Department of Orthopaedics and Traumatology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

出版信息

Acta Orthop. 2020 Jun;91(3):341-346. doi: 10.1080/17453674.2020.1732016. Epub 2020 Feb 28.

DOI:10.1080/17453674.2020.1732016
PMID:32106736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8023874/
Abstract

Background and purpose - The pelvis is the 3rd most common site of skeletal metastases. In some cases, periacetabular lesions require palliative surgical management. We investigated functional outcome, complications, and implant and patient survival after a modified Harrington's procedure.Patients and methods - This retrospective cohort study included 89 cases of surgically treated periacetabular metastases. All patients were treated with the modified Harrington's procedure including a restoration ring. Lesions were classified according to Harrington. Functional outcome was assessed by Harris Hip Score (HHS) and Oxford Hip Score (OHS). Postoperative complications, and implant and patient survival are reported.Results - The overall postoperative functional outcome was good to fair (OHS 37 and HHS 76). Sex, age, survival > 6 and 12 months, and diagnosis of the primary tumor affected functional outcome. Overall implant survival was 96% (95% Cl 88-100) at 1 year, 2 years, and 5 years; only 1 acetabular implant required revision. Median patient survival was 8 months (0-125). 10/89 patients had postoperative complications: 6 major complications, leading to revision surgery, and 4 minor complications.Interpretation - Our modified Harrington's procedure with a restoration ring to achieve stable fixation, constrained acetabular cup to prevent dislocation, and antegrade iliac screws to prevent cranial protrusion is a reliable reconstruction for periacetabular metastases and results in a good functional outcome in patients with prolonged survival. A standardized procedure and low complication rate encourage the use of this method for all Harrington class defects.

摘要

背景与目的 - 骨盆是骨骼转移的第 3 常见部位。在某些情况下,需要姑息性手术治疗髋臼周围病变。我们研究了改良哈林顿手术治疗髋臼周围转移瘤的功能结果、并发症以及植入物和患者的生存率。

患者和方法 - 这是一项回顾性队列研究,纳入了 89 例接受手术治疗的髋臼周围转移瘤患者。所有患者均接受改良哈林顿手术治疗,包括修复环。根据哈林顿分类对病变进行分类。采用 Harris 髋关节评分(HHS)和牛津髋关节评分(OHS)评估功能结果。报告术后并发症、植入物和患者生存率。

结果 - 整体术后功能结果为良好至一般(OHS 为 37,HHS 为 76)。性别、年龄、生存时间>6 个月和>12 个月以及原发性肿瘤的诊断影响功能结果。1 年、2 年和 5 年的总体植入物生存率为 96%(95%CI 88-100),仅 1 个髋臼植入物需要翻修。中位患者生存率为 8 个月(0-125)。89 例患者中有 10 例发生术后并发症:6 例严重并发症导致翻修手术,4 例轻微并发症。

结论 - 我们采用改良哈林顿手术治疗髋臼周围转移瘤,使用修复环实现稳定固定、使用约束性髋臼杯防止脱位以及使用顺行髂骨螺钉防止颅侧突出,这是一种可靠的重建方法,可获得良好的功能结果,且患者生存时间延长。标准化的手术程序和低并发症发生率鼓励对所有哈林顿缺陷类型使用这种方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d544/8023874/79702cada538/IORT_A_1732016_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d544/8023874/79702cada538/IORT_A_1732016_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d544/8023874/79702cada538/IORT_A_1732016_F0001_B.jpg

相似文献

1
Modified Harrington's procedure for periacetabular metastases in 89 cases: a reliable method for cancer patients with good functional outcome, especially with long expected survival.89 例髋臼周围转移瘤改良 Harrington 手术:一种可靠的方法,可获得良好的功能结果,特别是对预期生存时间较长的癌症患者。
Acta Orthop. 2020 Jun;91(3):341-346. doi: 10.1080/17453674.2020.1732016. Epub 2020 Feb 28.
2
LUMiC Endoprosthetic Reconstruction After Periacetabular Tumor Resection: Short-term Results.髋臼周围肿瘤切除术后的LUMiC人工关节重建:短期结果
Clin Orthop Relat Res. 2017 Mar;475(3):686-695. doi: 10.1007/s11999-016-4805-4.
3
Acetabular Reconstruction With Femoral Head Autograft After Intraarticular Resection of Periacetabular Tumors is Durable at Short-term Followup.髋臼周围肿瘤关节内切除术后采用自体股骨头移植进行髋臼重建在短期随访中效果持久。
Clin Orthop Relat Res. 2017 Dec;475(12):3060-3070. doi: 10.1007/s11999-017-5505-4. Epub 2017 Sep 25.
4
Acetabular reconstruction with an ice-cream cone prosthesis following resection of pelvic tumors: Does computer navigation improve surgical outcome?骨盆肿瘤切除术后采用冰淇淋锥型假体行髋臼重建:计算机导航是否能改善手术效果?
J Surg Oncol. 2020 Jun;121(7):1104-1114. doi: 10.1002/jso.25882. Epub 2020 Mar 9.
5
[Modified Harrington Procedure in the Treatment of Extensive Tumor Defects of the Acetabulum].[改良哈灵顿手术治疗髋臼广泛肿瘤缺损]
Acta Chir Orthop Traumatol Cech. 2023;90(2):124-132.
6
Constrained total hip megaprosthesis for primary periacetabular tumors.髋臼周围原发性肿瘤的受限型全髋关节假体置换。
Clin Orthop Relat Res. 2013 Mar;471(3):741-9. doi: 10.1007/s11999-012-2625-8.
7
Functional outcome and complications following reconstruction for Harrington class II and III periacetabular metastasis.哈灵顿II级和III级髋臼周围转移瘤重建后的功能结果及并发症
World J Surg Oncol. 2015 Jan 12;13:4. doi: 10.1186/1477-7819-13-4.
8
Reconstruction of advanced periacetabular metastatic lesions with modified Harrington procedure.采用改良哈灵顿手术重建髋臼周围晚期转移性病变。
Acta Orthop Traumatol Turc. 2016;50(2):178-85. doi: 10.3944/AOTT.2015.15.0076.
9
The modified Harrington procedure for metastatic peri-acetabular bone destruction.改良 Harrington 术治疗髋关节周围转移骨破坏
Int Orthop. 2013 Oct;37(10):1981-5. doi: 10.1007/s00264-013-1940-3. Epub 2013 Jun 12.
10
Is a Modular Pedicle-hemipelvic Endoprosthesis Durable at Short Term in Patients Undergoing Enneking Type I + II Tumor Resections With or Without Sacroiliac Involvement?对于行 Enneking Ⅰ+Ⅱ型肿瘤切除术且(或)累及骶髂关节的患者,模块化经皮骨盆内固定系统在短期内是否耐用?
Clin Orthop Relat Res. 2018 Sep;476(9):1751-1761. doi: 10.1007/s11999.0000000000000121.

引用本文的文献

1
Periacetabular metastases: Proposed extension of the Harrington classification.髋臼周围转移瘤:对哈灵顿分类法的扩展建议
J Orthop. 2025 Jan 4;66:34-42. doi: 10.1016/j.jor.2025.01.003. eCollection 2025 Aug.
2
Comparison of Percutaneous Techniques for Stabilization of Osteolytic Lesions of the Periacetabular Region Due to Metastatic Bone Disease.转移性骨病所致髋臼周围区域溶骨性病变稳定的经皮技术比较
Ann Surg Oncol. 2025 Mar;32(3):1529-1540. doi: 10.1245/s10434-024-16627-5. Epub 2024 Dec 4.
3
Safety and efficacy of combined acetabular reconstruction and microwave ablation in the treatment of periacetabular metastatic disease: a retrospective clinical evaluation.

本文引用的文献

1
Is an Acetabular Cage and Cement Fixation Sufficiently Durable for the Treatment of Destructive Acetabular Metastases?髋臼笼和水泥固定治疗破坏性髋臼转移瘤是否足够耐用?
Clin Orthop Relat Res. 2019 Jun;477(6):1459-1465. doi: 10.1097/CORR.0000000000000725.
2
Multidisciplinary Approach for Bone Metastasis: A Review.骨转移的多学科治疗方法:综述
Cancers (Basel). 2018 May 24;10(6):156. doi: 10.3390/cancers10060156.
3
Treatment Success Following Joint Arthroplasty: Defining Thresholds for the Oxford Hip and Knee Scores.关节置换术后的治疗成功:定义牛津髋关节和膝关节评分的阈值。
髋臼重建联合微波消融治疗髋臼周围转移性疾病的安全性和有效性:一项回顾性临床评估
Front Oncol. 2024 Oct 31;14:1484876. doi: 10.3389/fonc.2024.1484876. eCollection 2024.
4
Is surgery without curettage effective for periacetabular Metastasis? Insights from a survival study of 93 patients.不进行刮除术的手术治疗对髋臼周围转移瘤是否有效?来自93例患者生存研究的见解。
J Bone Oncol. 2024 Oct 10;49:100643. doi: 10.1016/j.jbo.2024.100643. eCollection 2024 Dec.
5
A Prospective Study of the IlluminOss Photodynamic Nail System for Pelvic Stabilization: Treatment of Impending and Actual Fractures from Metastatic Bone Disease, Multiple Myeloma, and Primary Bone Lymphoma.用于骨盆稳定的IlluminOss光动力钉系统的前瞻性研究:治疗转移性骨病、多发性骨髓瘤和原发性骨淋巴瘤的潜在骨折和实际骨折。
JB JS Open Access. 2024 Sep 13;9(3). doi: 10.2106/JBJS.OA.24.00016. eCollection 2024 Jul-Sep.
6
Global research development of chondrosarcoma from 2003 to 2022: a bibliometric analysis.2003年至2022年软骨肉瘤的全球研究进展:一项文献计量分析
Front Pharmacol. 2024 Aug 2;15:1431958. doi: 10.3389/fphar.2024.1431958. eCollection 2024.
7
The Modified Harrington Procedure for Metastatic Peri-Acetabular Bone Lesion Using a Novel Highly Porous Titanium Revision Shell with Long Lever Arm Screw.采用新型长柄螺钉的高多孔钛翻修外壳对髋臼周围转移性骨病变行改良 Harrington 手术。
Medicina (Kaunas). 2024 Jun 26;60(7):1047. doi: 10.3390/medicina60071047.
8
Outcomes Following Pedestal Cup Reconstruction of (Impending) Pathological Fractures of the Acetabulum due to Metastatic Bone Disease.转移性骨病所致髋臼(即将发生的)病理性骨折行髋臼杯重建后的疗效
Indian J Surg Oncol. 2024 Jun;15(2):428-436. doi: 10.1007/s13193-024-01917-x. Epub 2024 Mar 16.
9
Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases.经皮射频消融、骨成形术、强化及内固定治疗髋臼周围溶骨性转移瘤后的骨量变化
J Clin Med. 2023 Jul 11;12(14):4613. doi: 10.3390/jcm12144613.
10
Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions.后路 Harrington 手术治疗复杂髋臼转移性病变患者的功能和生存结局。
Curr Oncol. 2022 Aug 19;29(8):5875-5890. doi: 10.3390/curroncol29080464.
J Arthroplasty. 2018 Aug;33(8):2392-2397. doi: 10.1016/j.arth.2018.03.062. Epub 2018 Mar 30.
4
Total Hip Arthroplasty for Periacetabular Metastatic Disease. An Original Technique of Reconstruction According to the Harrington Classification.髋臼周围转移瘤全髋关节置换术。根据哈灵顿分类的重建原创技术。
J Arthroplasty. 2018 Aug;33(8):2546-2555. doi: 10.1016/j.arth.2018.02.096. Epub 2018 Mar 17.
5
Surgical treatment for periacetabular metastatic lesions.髋臼周围转移性病变的外科治疗。
Eur J Surg Oncol. 2017 Sep;43(9):1727-1732. doi: 10.1016/j.ejso.2017.03.018. Epub 2017 Apr 8.
6
Outcome after Surgery for Metastases to the Pelvic Bone: A Single Institutional Experience.骨盆骨转移瘤手术后的结局:单机构经验
Clin Orthop Surg. 2017 Mar;9(1):116-125. doi: 10.4055/cios.2017.9.1.116. Epub 2017 Feb 13.
7
Reconstruction of advanced periacetabular metastatic lesions with modified Harrington procedure.采用改良哈灵顿手术重建髋臼周围晚期转移性病变。
Acta Orthop Traumatol Turc. 2016;50(2):178-85. doi: 10.3944/AOTT.2015.15.0076.
8
Reconstruction of metastatic acetabular defects using a modified Harrington procedure.采用改良哈林顿手术重建转移性髋臼缺损。
Acta Orthop. 2015;86(6):690-4. doi: 10.3109/17453674.2015.1077308. Epub 2015 Jul 28.
9
Percutaneous Acetabuloplasty Compared With Open Reconstruction for Extensive Periacetabular Carcinoma Metastases.经皮髋臼成形术与开放性重建术治疗广泛髋臼周围癌转移的比较
J Arthroplasty. 2015 Sep;30(9):1586-91. doi: 10.1016/j.arth.2015.02.022. Epub 2015 Feb 27.
10
Outcomes of Modified Harrington Reconstructions for Nonprimary Periacetabular Tumors: An Effective and Inexpensive Technique.改良哈灵顿重建术治疗非原发性髋臼周围肿瘤的疗效:一种有效且经济的技术。
Ann Surg Oncol. 2015 Nov;22(12):3921-8. doi: 10.1245/s10434-015-4507-2. Epub 2015 Mar 17.