Division of Reproductive Sciences, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Health System; and TRIO Fertility, Toronto, Ontario, Canada.
Fertil Steril. 2020 Feb;113(2):248-251. doi: 10.1016/j.fertnstert.2019.12.008.
Endometrial receptivity appears to be as important as chromosomal normality in determining embryo implantation and pregnancy outcome, because the ongoing pregnancy rate with transfer of preimplantation genetic testing for aneuploidy euploid blastocysts is ∼50%. This Views and Reviews article focuses on our current knowledge of the biology of endometrial receptivity and on the role of both invasive (endometrial biopsy) and noninvasive (ultrasound) assessment in successful endometrial preparation for frozen-thawed embryo transfer.
子宫内膜容受性似乎与染色体正常性一样重要,决定胚胎着床和妊娠结局,因为移植非整倍体胚胎的种植率约为 50%。这篇观点和综述文章主要关注我们目前对子宫内膜容受性生物学的认识,以及侵袭性(子宫内膜活检)和非侵袭性(超声)评估在冷冻胚胎解冻移植中成功准备子宫内膜的作用。