甲硝唑在择期结肠手术中预防和治疗拟杆菌感染的应用
Metronidazole in prevention and treatment of bacteroides infections in elective colonic surgery.
作者信息
Willis A T, Ferguson I R, Jones P H, Phillips K D, Tearle P V, Fiddian R V, Graham D F, Harland D H, Hughes D F, Knight D, Mee W M, Pashby N, Rothwell-Jackson R L, Sachdeva A K, Sutch I, Kilbey C, Edwards D
出版信息
Br Med J. 1977 Mar 5;1(6061):607-10. doi: 10.1136/bmj.1.6061.607.
Abstract
A double-blind randomised trial was carried out among 46 patients undergoing elective colonic surgery; 27 patients received prophylactic metronidazole and 19 received placebo. Anaerobic infections did not develop in any of the metronidazole-treated patients, but did develop in 11 (58%) of 19 controls who were subsequently successfully treated with metronidazole.
摘要
对46例接受择期结肠手术的患者进行了一项双盲随机试验；27例患者接受预防性甲硝唑治疗，19例接受安慰剂治疗。接受甲硝唑治疗的患者均未发生厌氧菌感染，但19例对照组中有11例（58%）发生了厌氧菌感染，这些患者随后用甲硝唑成功治疗。
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